Topographic maps within brodmann's area 5 of macaque monkeys

Adele M H Seelke, Jeffrey J. Padberg, Elizabeth Disbrow, Shawn M. Purnell, Gregg Recanzone, Leah Krubitzer

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Brodmann's area 5 has traditionally included the rostral bank of the intraparietal sulcus (IPS) as well as posterior portions of the postcentral gyrus and medial wall. However, different portions of this large architectonic zone may serve different functions related to reaching and grasping behaviors. The current study used multiunit recording techniques in anesthetized macaque monkeys to survey a large extent of the rostral bank of the IPS so that hundreds of recording sites could be used to determine the functional subdivisions and topographic organization of cortical areas in this region. We identified a lateral area on the rostral IPS that we term area 5L. Area 5L contains neurons with receptive fields on mostly the shoulder, forelimb, and digits, with no apparent representation of other body parts. Thus, there is a large magnification of the forelimb. Receptive fields for neurons in this region often contain multiple joints of the forelimb or multiple digits, which results in imprecise topography or fractures in map organization. Our results provide the first overall topographic map of area 5L obtained in individual macaque monkeys and suggest that this region is distinct from more medial portions of the IPS.

Original languageEnglish (US)
Pages (from-to)1834-1850
Number of pages17
JournalCerebral Cortex
Volume22
Issue number8
DOIs
StatePublished - Aug 2012

Fingerprint

Parietal Lobe
Macaca
Haplorhini
Forelimb
Neurons
Somatosensory Cortex
Human Body
Joints
Organizations

Keywords

  • area 2
  • area 5
  • medial intraparietal cortex
  • posterior parietal cortex
  • primates

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

Seelke, A. M. H., Padberg, J. J., Disbrow, E., Purnell, S. M., Recanzone, G., & Krubitzer, L. (2012). Topographic maps within brodmann's area 5 of macaque monkeys. Cerebral Cortex, 22(8), 1834-1850. https://doi.org/10.1093/cercor/bhr257

Topographic maps within brodmann's area 5 of macaque monkeys. / Seelke, Adele M H; Padberg, Jeffrey J.; Disbrow, Elizabeth; Purnell, Shawn M.; Recanzone, Gregg; Krubitzer, Leah.

In: Cerebral Cortex, Vol. 22, No. 8, 08.2012, p. 1834-1850.

Research output: Contribution to journalArticle

Seelke, AMH, Padberg, JJ, Disbrow, E, Purnell, SM, Recanzone, G & Krubitzer, L 2012, 'Topographic maps within brodmann's area 5 of macaque monkeys', Cerebral Cortex, vol. 22, no. 8, pp. 1834-1850. https://doi.org/10.1093/cercor/bhr257
Seelke AMH, Padberg JJ, Disbrow E, Purnell SM, Recanzone G, Krubitzer L. Topographic maps within brodmann's area 5 of macaque monkeys. Cerebral Cortex. 2012 Aug;22(8):1834-1850. https://doi.org/10.1093/cercor/bhr257
Seelke, Adele M H ; Padberg, Jeffrey J. ; Disbrow, Elizabeth ; Purnell, Shawn M. ; Recanzone, Gregg ; Krubitzer, Leah. / Topographic maps within brodmann's area 5 of macaque monkeys. In: Cerebral Cortex. 2012 ; Vol. 22, No. 8. pp. 1834-1850.
@article{ff92c6a67b6243539434c9369bbb312c,
title = "Topographic maps within brodmann's area 5 of macaque monkeys",
abstract = "Brodmann's area 5 has traditionally included the rostral bank of the intraparietal sulcus (IPS) as well as posterior portions of the postcentral gyrus and medial wall. However, different portions of this large architectonic zone may serve different functions related to reaching and grasping behaviors. The current study used multiunit recording techniques in anesthetized macaque monkeys to survey a large extent of the rostral bank of the IPS so that hundreds of recording sites could be used to determine the functional subdivisions and topographic organization of cortical areas in this region. We identified a lateral area on the rostral IPS that we term area 5L. Area 5L contains neurons with receptive fields on mostly the shoulder, forelimb, and digits, with no apparent representation of other body parts. Thus, there is a large magnification of the forelimb. Receptive fields for neurons in this region often contain multiple joints of the forelimb or multiple digits, which results in imprecise topography or fractures in map organization. Our results provide the first overall topographic map of area 5L obtained in individual macaque monkeys and suggest that this region is distinct from more medial portions of the IPS.",
keywords = "area 2, area 5, medial intraparietal cortex, posterior parietal cortex, primates",
author = "Seelke, {Adele M H} and Padberg, {Jeffrey J.} and Elizabeth Disbrow and Purnell, {Shawn M.} and Gregg Recanzone and Leah Krubitzer",
year = "2012",
month = "8",
doi = "10.1093/cercor/bhr257",
language = "English (US)",
volume = "22",
pages = "1834--1850",
journal = "Cerebral Cortex",
issn = "1047-3211",
publisher = "Oxford University Press",
number = "8",

}

TY - JOUR

T1 - Topographic maps within brodmann's area 5 of macaque monkeys

AU - Seelke, Adele M H

AU - Padberg, Jeffrey J.

AU - Disbrow, Elizabeth

AU - Purnell, Shawn M.

AU - Recanzone, Gregg

AU - Krubitzer, Leah

PY - 2012/8

Y1 - 2012/8

N2 - Brodmann's area 5 has traditionally included the rostral bank of the intraparietal sulcus (IPS) as well as posterior portions of the postcentral gyrus and medial wall. However, different portions of this large architectonic zone may serve different functions related to reaching and grasping behaviors. The current study used multiunit recording techniques in anesthetized macaque monkeys to survey a large extent of the rostral bank of the IPS so that hundreds of recording sites could be used to determine the functional subdivisions and topographic organization of cortical areas in this region. We identified a lateral area on the rostral IPS that we term area 5L. Area 5L contains neurons with receptive fields on mostly the shoulder, forelimb, and digits, with no apparent representation of other body parts. Thus, there is a large magnification of the forelimb. Receptive fields for neurons in this region often contain multiple joints of the forelimb or multiple digits, which results in imprecise topography or fractures in map organization. Our results provide the first overall topographic map of area 5L obtained in individual macaque monkeys and suggest that this region is distinct from more medial portions of the IPS.

AB - Brodmann's area 5 has traditionally included the rostral bank of the intraparietal sulcus (IPS) as well as posterior portions of the postcentral gyrus and medial wall. However, different portions of this large architectonic zone may serve different functions related to reaching and grasping behaviors. The current study used multiunit recording techniques in anesthetized macaque monkeys to survey a large extent of the rostral bank of the IPS so that hundreds of recording sites could be used to determine the functional subdivisions and topographic organization of cortical areas in this region. We identified a lateral area on the rostral IPS that we term area 5L. Area 5L contains neurons with receptive fields on mostly the shoulder, forelimb, and digits, with no apparent representation of other body parts. Thus, there is a large magnification of the forelimb. Receptive fields for neurons in this region often contain multiple joints of the forelimb or multiple digits, which results in imprecise topography or fractures in map organization. Our results provide the first overall topographic map of area 5L obtained in individual macaque monkeys and suggest that this region is distinct from more medial portions of the IPS.

KW - area 2

KW - area 5

KW - medial intraparietal cortex

KW - posterior parietal cortex

KW - primates

UR - http://www.scopus.com/inward/record.url?scp=84863686421&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863686421&partnerID=8YFLogxK

U2 - 10.1093/cercor/bhr257

DO - 10.1093/cercor/bhr257

M3 - Article

C2 - 21955920

AN - SCOPUS:84863686421

VL - 22

SP - 1834

EP - 1850

JO - Cerebral Cortex

JF - Cerebral Cortex

SN - 1047-3211

IS - 8

ER -