Topiramate for phantom limb pain: A time-series analysis

R. Norman Harden, Tim T. Houle, Thomas A. Remble, Wendy Lin, Kenten Wang, Samuel Saltz

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

There is growing evidence of topiramate's efficacy in treating neuropathic pain. This article reports a detailed analysis of the response of four amputee subjects with phantom limb pain. Individual time-series analyses revealed that three out of four amputee participants receiving topiramate had statistically significant decreases in pain, with the peak effect noted at 800 mg daily. This analysis supports a hypothesis that topiramate may be effective in reducing phantom limb pain, and suggests a definitive study is indicated.

Original languageEnglish (US)
Pages (from-to)375-378
Number of pages4
JournalPain Medicine
Volume6
Issue number5
DOIs
StatePublished - Sep 2005
Externally publishedYes

Fingerprint

Phantom Limb
Amputees
Neuralgia
Pain
topiramate

Keywords

  • Antiepileptics
  • Phantom Pain
  • Time-Series Analysis
  • Topiramate

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Harden, R. N., Houle, T. T., Remble, T. A., Lin, W., Wang, K., & Saltz, S. (2005). Topiramate for phantom limb pain: A time-series analysis. Pain Medicine, 6(5), 375-378. https://doi.org/10.1111/j.1526-4637.2005.00060.x

Topiramate for phantom limb pain : A time-series analysis. / Harden, R. Norman; Houle, Tim T.; Remble, Thomas A.; Lin, Wendy; Wang, Kenten; Saltz, Samuel.

In: Pain Medicine, Vol. 6, No. 5, 09.2005, p. 375-378.

Research output: Contribution to journalArticle

Harden, RN, Houle, TT, Remble, TA, Lin, W, Wang, K & Saltz, S 2005, 'Topiramate for phantom limb pain: A time-series analysis', Pain Medicine, vol. 6, no. 5, pp. 375-378. https://doi.org/10.1111/j.1526-4637.2005.00060.x
Harden RN, Houle TT, Remble TA, Lin W, Wang K, Saltz S. Topiramate for phantom limb pain: A time-series analysis. Pain Medicine. 2005 Sep;6(5):375-378. https://doi.org/10.1111/j.1526-4637.2005.00060.x
Harden, R. Norman ; Houle, Tim T. ; Remble, Thomas A. ; Lin, Wendy ; Wang, Kenten ; Saltz, Samuel. / Topiramate for phantom limb pain : A time-series analysis. In: Pain Medicine. 2005 ; Vol. 6, No. 5. pp. 375-378.
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