Topical tretinoin, another failure in the pursuit of practical chemoprevention for non-melanoma skin cancer

Peggy Wu, Robert S. Stern

Research output: Contribution to journalReview article

8 Citations (Scopus)

Abstract

Given the high incidence of non-melanoma skin cancer (NMSC), a preventative intervention would be desirable. Except for regular sunscreen use, the quest for chemoprevention of NMSC in the general population has been unsuccessful. Weinstock et al. assessed the effects of 0.1% topical tretinoin on NMSC. Like earlier efforts at chemoprevention, this study failed to show therapeutic benefit. Future successful preventative strategies will likely rely on short-term, intermittent therapy or treatments used for other common indications.

Original languageEnglish (US)
Pages (from-to)1532-1535
Number of pages4
JournalJournal of Investigative Dermatology
Volume132
Issue number6
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

Fingerprint

Chemoprevention
Skin Neoplasms
Tretinoin
Skin
Sun hoods
Sunscreening Agents
Therapeutics
Incidence
Population

ASJC Scopus subject areas

  • Biochemistry
  • Medicine(all)
  • Molecular Biology
  • Dermatology
  • Cell Biology

Cite this

Topical tretinoin, another failure in the pursuit of practical chemoprevention for non-melanoma skin cancer. / Wu, Peggy; Stern, Robert S.

In: Journal of Investigative Dermatology, Vol. 132, No. 6, 01.06.2012, p. 1532-1535.

Research output: Contribution to journalReview article

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