Topical negative pressure devices: Use for enhancement of healing chronic wounds

Miki Shirakawa, Roslyn Rivkah Isseroff

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Chronic wounds present a significant challenge, because there are few available treatment options for timely healing. Topical negative pressure devices have been used in a number of different types of wounds, including chronic wounds. They are believed to hasten wound healing by (1) maintaining a moist environment, (2) removing wound exudates, (3) increasing local blood flow, (4) increasing granulation tissue formation, (5) applying mechanical pressure to promote wound closure, and (6) reducing bacterial loads in the wound. Multiple nonrandomized, noncontrolled studies have reported that the use of these devices results in faster healing times and more successful closures. Five small randomized, controlled trials have also shown favorable outcomes with the use of topical negative pressure devices compared with conventional treatment. Adverse effects include discomfort, pain, and excessive tissue growth into the dressing. Complications are limited if the device is used properly. In light of the current treatment options, topical negative pressure devices may be considered useful as adjuvant therapy for chronic wounds; however, there is inadequate definitive evidence that wound healing is substantially better with these devices than with traditional therapy.

Original languageEnglish (US)
Pages (from-to)1449-1453
Number of pages5
JournalArchives of Dermatology
Volume141
Issue number11
DOIs
StatePublished - Nov 2005

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Wound Healing
Pressure
Equipment and Supplies
Wounds and Injuries
Nociceptive Pain
Therapeutics
Granulation Tissue
Bacterial Load
Exudates and Transudates
Bandages
Randomized Controlled Trials
Growth

ASJC Scopus subject areas

  • Dermatology

Cite this

Topical negative pressure devices : Use for enhancement of healing chronic wounds. / Shirakawa, Miki; Isseroff, Roslyn Rivkah.

In: Archives of Dermatology, Vol. 141, No. 11, 11.2005, p. 1449-1453.

Research output: Contribution to journalArticle

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