Tonotopy in human auditory cortex examined with functional magnetic resonance imaging

C. Mark Wessinger; Michael H. Buonocore; Clif L. Kussmaul; George R Mangun

doi:10.1002/(SICI)1097-0193(1997)5:1<18::AID-HBM3>3.0.CO;2-Q

Tonotopy in human auditory cortex examined with functional magnetic resonance imaging

C. Mark Wessinger, Michael H. Buonocore, Clif L. Kussmaul, George R Mangun

Research output: Contribution to journal › Article › peer-review

142 Scopus citations

Abstract

Tonotopic organization within the human auditory cortex was investigated with functional magnetic resonance imaging (fMRI) using the blond oxygenation level-dependent (BOLD) contrast mechanism. Single-frequency pulsed tones were alternated with no-tone conditions to elicit stimulus-specific functional activity. Differential frequency-specific activity was imaged within the auditory cortex. Activations for high-frequency tones were located more posteriorly and medially than those for low-frequency tones. Such a pattern is consistent with descriptions of tonotopic organization suggested by other nonneuroimaging methodologies used with human and nonhuman primates. Furthermore, these results demonstrate that fMRI can be used to reliably investigate functional organization of the human auditory cortex.

Original language	English (US)
Pages (from-to)	18-25
Number of pages	8
Journal	Human Brain Mapping
Volume	5
Issue number	1
DOIs	https://doi.org/10.1002/(SICI)1097-0193(1997)5:1<18::AID-HBM3>3.0.CO;2-Q
State	Published - 1997

Keywords

auditory cortex
blood oxygenation level-dependent
BOLD
functional magnetic resonance imaging
tonotopy

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Clinical Neurology
Neuroscience(all)

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10.1002/(SICI)1097-0193(1997)5:1<18::AID-HBM3>3.0.CO;2-Q

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Tonotopy in human auditory cortex examined with functional magnetic resonance imaging

Abstract

Keywords

ASJC Scopus subject areas

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