Toll-like receptors in wound healing: Location, accessibility, and timing

Mohan R. Dasu, Roslyn Rivkah Isseroff

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Toll-like receptors (TLRs) are considered to be the first responders in the defense against invading pathogens. TLR engagement by ligands triggers inflammatory responses in injury and trauma, and thus can impair or contribute to the healing process, depending on TLRs' expression pattern, cellular localization, signaling, and deployment of inflammatory responses. Understanding these attributes could improve therapeutic strategies for treating chronic wounds.

Original languageEnglish (US)
Pages (from-to)1955-1958
Number of pages4
JournalJournal of Investigative Dermatology
Volume132
Issue number8
DOIs
StatePublished - Aug 2012

ASJC Scopus subject areas

  • Dermatology
  • Biochemistry
  • Cell Biology
  • Molecular Biology

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