Time-resolved laser induced fluorescence of normal and atherosclerotic coronary artery

Laura Marcu, Jean Michel I Maarek, Michael C. Fishbein, Warren S. Grundfest

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

The spectro-temporal fluorescence emission of normal and diseased coronary arteries with graded levels of atherosclerosis was investigated. Fluorescence emission of 58 excised human coronary artery samples was induced with N 2 laser pulses and detected with a MCP-PMT connected to a digital oscilloscope. It was found that the analysis of the temporal characteristics of fluorescence can be used to differentiate between coronary lesions and normal coronary wall. The time domain information complements the spectral domain intensity data for improved differentiation between graded levels of coronary lesions.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
PublisherSociety of Photo-Optical Instrumentation Engineers
Pages182-191
Number of pages10
Volume3600
StatePublished - 1999
Externally publishedYes
EventProceedings of the 1999 Biomedical Imaging: Reporters, Dyes, and Instrumentation - San Jose, CA, USA
Duration: Jan 26 1999Jan 28 1999

Other

OtherProceedings of the 1999 Biomedical Imaging: Reporters, Dyes, and Instrumentation
CitySan Jose, CA, USA
Period1/26/991/28/99

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

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  • Cite this

    Marcu, L., Maarek, J. M. I., Fishbein, M. C., & Grundfest, W. S. (1999). Time-resolved laser induced fluorescence of normal and atherosclerotic coronary artery. In Proceedings of SPIE - The International Society for Optical Engineering (Vol. 3600, pp. 182-191). Society of Photo-Optical Instrumentation Engineers.