Abstract
Cats were given 6000 rads to a volume of approximately 0.25 cm3 and followed for blood-brain barrier (B-BB) breakdown by the penicillin-EEG method. They showed a variation of about 1 to 20 days before the onset of B-BB breakdown and of 20 to 80 days for recovery. This demonstrates the central role of endothelium damage and loss of B-BB function in the pathogenesis of radiation damage to the central nervous system.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 310-314 |
| Number of pages | 5 |
| Journal | Experimental Neurology |
| Volume | 73 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1981 |
ASJC Scopus subject areas
- Neuroscience(all)
- Neurology
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Remler, M. P., & Marcussen, W. H. (1981). Time course of early delayed blood-brain barrier changes in individual cats after lonizing radiation. Experimental Neurology, 73(1), 310-314. https://doi.org/10.1016/0014-4886(81)90065-0