Thyrotropin-releasing hormone stimulation testing in healthy dogs.

J. V. Evinger, Richard W Nelson, G. D. Bottoms

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Serum triiodothyronine (T3) and thyroxine (T4) concentrations were determined after IV administration of 200 micrograms of thyrotropin-releasing hormone (TRH) to 10 healthy euthyroid dogs. Significant (P less than 0.05) changes were not found in the T3 concentration throughout an 8-hour sampling interval. All dogs had a significant increase (P less than 0.05) in the T4 concentration at 4, 5, 6, 7, and 8 hours after TRH administration. The largest increase in the serum T4 concentration occurred 4 hours after TRH injection. From 4 to 8 hours after TRH administration, the mean increase above basal T4 concentrations was 13.9 +/- 5.4 ng/ml.

Original languageEnglish (US)
Pages (from-to)1323-1325
Number of pages3
JournalAmerican Journal of Veterinary Research
Issue number6
StatePublished - Jun 1985
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)


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