Three-year visual acuity outcomes after Descemet's stripping automated endothelial keratoplasty

Jennifer Li, Mark A. Terry, Jeffrey Goshe, David Davis-Boozer, Neda Shamie

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Purpose: To evaluate the long-term improvement of visual acuity after Descemet's stripping automated endothelial keratoplasty (DSAEK) surgery. Design: Retrospective analysis of a noncomparative, interventional case series. Participants: One hundred eight patients undergoing DSAEK surgery for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy without other ocular comorbidities who completed a full 3-year follow-up period. Methods: Postoperative best spectacle-corrected visual acuity (BSCVA) was recorded at 6, 12, 24, and 36 months. Improvement in BSCVA between each time point was evaluated using paired-samples t tests. Subanalysis evaluating the percentage of eyes achieving a BSCVA of 20/20, 20/25, 20/30, and 20/40 at each time point was performed. Main Outcome Measures: Improvement in postoperative BSCVA. Results: There was a statistically significant trend toward improvement in average BSCVA with time at postoperative month 6 and postoperative years 2 and 3. There were also increasing proportions of eyes reaching vision of 20/20, 20/25, and 20/30 from 6 months to 1 year, 1 year to 2 years, and 2 years to 3 years. The percentage of patients achieving 20/25 BSCVA improved from 36.1% at 6 months to 70.4% at 3 years after surgery. A similar increase in the percentage of patients reaching a BSCVA of 20/20 after DSAEK surgery also was observed from 11.1% at 6 months to approximately 47.2% at 3 years. Conclusions: There is gradual improvement of visual acuity over time after DSAEK surgery for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy in patients without other vision-limiting ocular comorbidities. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references.

Original languageEnglish (US)
Pages (from-to)1126-1129
Number of pages4
JournalOphthalmology
Volume119
Issue number6
DOIs
StatePublished - Jun 2012
Externally publishedYes

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Descemet Stripping Endothelial Keratoplasty
Visual Acuity
Disclosure
Comorbidity
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Three-year visual acuity outcomes after Descemet's stripping automated endothelial keratoplasty. / Li, Jennifer; Terry, Mark A.; Goshe, Jeffrey; Davis-Boozer, David; Shamie, Neda.

In: Ophthalmology, Vol. 119, No. 6, 06.2012, p. 1126-1129.

Research output: Contribution to journalArticle

Li, Jennifer ; Terry, Mark A. ; Goshe, Jeffrey ; Davis-Boozer, David ; Shamie, Neda. / Three-year visual acuity outcomes after Descemet's stripping automated endothelial keratoplasty. In: Ophthalmology. 2012 ; Vol. 119, No. 6. pp. 1126-1129.
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abstract = "Purpose: To evaluate the long-term improvement of visual acuity after Descemet's stripping automated endothelial keratoplasty (DSAEK) surgery. Design: Retrospective analysis of a noncomparative, interventional case series. Participants: One hundred eight patients undergoing DSAEK surgery for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy without other ocular comorbidities who completed a full 3-year follow-up period. Methods: Postoperative best spectacle-corrected visual acuity (BSCVA) was recorded at 6, 12, 24, and 36 months. Improvement in BSCVA between each time point was evaluated using paired-samples t tests. Subanalysis evaluating the percentage of eyes achieving a BSCVA of 20/20, 20/25, 20/30, and 20/40 at each time point was performed. Main Outcome Measures: Improvement in postoperative BSCVA. Results: There was a statistically significant trend toward improvement in average BSCVA with time at postoperative month 6 and postoperative years 2 and 3. There were also increasing proportions of eyes reaching vision of 20/20, 20/25, and 20/30 from 6 months to 1 year, 1 year to 2 years, and 2 years to 3 years. The percentage of patients achieving 20/25 BSCVA improved from 36.1{\%} at 6 months to 70.4{\%} at 3 years after surgery. A similar increase in the percentage of patients reaching a BSCVA of 20/20 after DSAEK surgery also was observed from 11.1{\%} at 6 months to approximately 47.2{\%} at 3 years. Conclusions: There is gradual improvement of visual acuity over time after DSAEK surgery for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy in patients without other vision-limiting ocular comorbidities. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references.",
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