Thinking outside the synapse: Glycine at extrasynaptic NMDA receptors

John Gray, Roger A. Nicoll

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

In this issue, Papouin et al. show that glycine is the endogenous coagonist for extrasynaptic NMDA receptors (NMDARs), unlike at synapses where the coagonist is d-serine. By enzymatically degrading endogenous glycine, they begin to address the enigmatic physiological and pathological roles for extrasynaptic NMDARs.

Original languageEnglish (US)
Pages (from-to)455-456
Number of pages2
JournalCell
Volume150
Issue number3
DOIs
StatePublished - Aug 3 2012
Externally publishedYes

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N-Methyl-D-Aspartate Receptors
Synapses
Glycine
Serine

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Thinking outside the synapse : Glycine at extrasynaptic NMDA receptors. / Gray, John; Nicoll, Roger A.

In: Cell, Vol. 150, No. 3, 03.08.2012, p. 455-456.

Research output: Contribution to journalArticle

Gray, John ; Nicoll, Roger A. / Thinking outside the synapse : Glycine at extrasynaptic NMDA receptors. In: Cell. 2012 ; Vol. 150, No. 3. pp. 455-456.
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