Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels

Weiping Lin; Ming Hu; You Lo Hsieh; Mark J. Kurth; John M. Krochta

Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels

Weiping Lin, Ming Hu, You Lo Hsieh, Mark J. Kurth, John M. Krochta

Chemistry

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

A series of new thermosensitive polymer hydrogels were prepared by reacting acylated poly(ethylene glycol) bis(carboxymethyl) ether (PEGBCOCl) with lactitol-based polyether polyols (LPEP). The polyether polyols were generated from propoxylation of lactitol and have molecular weights ranging from 1337 to 4055 g/mol. The hydrogels absorb water up to 1000% of their dry weight and expel free water at temperatures at and above 30°C. The wide ranging swelling behavior and excellent thermosensitivity depend closely on the degree of crosslinking and the propylene oxide lengths in the polyols. Differential scanning calorimetry of the hydrogels showed two endotherms associated with the phase transitions of PO and EO segments in the hydrogel structures.

Original language	English (US)
Pages (from-to)	979-984
Number of pages	6
Journal	Journal of Polymer Science, Part A: Polymer Chemistry
Volume	36
Issue number	6
State	Published - Apr 30 1998

Keywords

Hydrogel
Lactitol
PEO and PPO linkage
Polyether polyol
Swelling degree
Thermosensitivity

ASJC Scopus subject areas

Materials Chemistry
Polymers and Plastics

Fingerprint Dive into the research topics of 'Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels'. Together they form a unique fingerprint.

Cite this

@article{05bf9b8caecb4da6b9c6f2915a65423f,

title = "Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels",

abstract = "A series of new thermosensitive polymer hydrogels were prepared by reacting acylated poly(ethylene glycol) bis(carboxymethyl) ether (PEGBCOCl) with lactitol-based polyether polyols (LPEP). The polyether polyols were generated from propoxylation of lactitol and have molecular weights ranging from 1337 to 4055 g/mol. The hydrogels absorb water up to 1000% of their dry weight and expel free water at temperatures at and above 30°C. The wide ranging swelling behavior and excellent thermosensitivity depend closely on the degree of crosslinking and the propylene oxide lengths in the polyols. Differential scanning calorimetry of the hydrogels showed two endotherms associated with the phase transitions of PO and EO segments in the hydrogel structures.",

keywords = "Hydrogel, Lactitol, PEO and PPO linkage, Polyether polyol, Swelling degree, Thermosensitivity",

author = "Weiping Lin and Ming Hu and Hsieh, {You Lo} and Kurth, {Mark J.} and Krochta, {John M.}",

year = "1998",

month = apr,

day = "30",

language = "English (US)",

volume = "36",

pages = "979--984",

journal = "Journal of Polymer Science, Part A: Polymer Chemistry",

issn = "0887-624X",

publisher = "John Wiley and Sons Inc.",

number = "6",

}

TY - JOUR

T1 - Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels

AU - Lin, Weiping

AU - Hu, Ming

AU - Hsieh, You Lo

AU - Kurth, Mark J.

AU - Krochta, John M.

PY - 1998/4/30

Y1 - 1998/4/30

N2 - A series of new thermosensitive polymer hydrogels were prepared by reacting acylated poly(ethylene glycol) bis(carboxymethyl) ether (PEGBCOCl) with lactitol-based polyether polyols (LPEP). The polyether polyols were generated from propoxylation of lactitol and have molecular weights ranging from 1337 to 4055 g/mol. The hydrogels absorb water up to 1000% of their dry weight and expel free water at temperatures at and above 30°C. The wide ranging swelling behavior and excellent thermosensitivity depend closely on the degree of crosslinking and the propylene oxide lengths in the polyols. Differential scanning calorimetry of the hydrogels showed two endotherms associated with the phase transitions of PO and EO segments in the hydrogel structures.

AB - A series of new thermosensitive polymer hydrogels were prepared by reacting acylated poly(ethylene glycol) bis(carboxymethyl) ether (PEGBCOCl) with lactitol-based polyether polyols (LPEP). The polyether polyols were generated from propoxylation of lactitol and have molecular weights ranging from 1337 to 4055 g/mol. The hydrogels absorb water up to 1000% of their dry weight and expel free water at temperatures at and above 30°C. The wide ranging swelling behavior and excellent thermosensitivity depend closely on the degree of crosslinking and the propylene oxide lengths in the polyols. Differential scanning calorimetry of the hydrogels showed two endotherms associated with the phase transitions of PO and EO segments in the hydrogel structures.

KW - Hydrogel

KW - Lactitol

KW - PEO and PPO linkage

KW - Polyether polyol

KW - Swelling degree

KW - Thermosensitivity

UR - http://www.scopus.com/inward/record.url?scp=0032045667&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032045667&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0032045667

VL - 36

SP - 979

EP - 984

JO - Journal of Polymer Science, Part A: Polymer Chemistry

JF - Journal of Polymer Science, Part A: Polymer Chemistry

SN - 0887-624X

IS - 6

ER -

Thermosensitive lactitol-based polyether polyol (LPEP) hydrogels

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Cite this