Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering

J. P. Fisher, S. Jo, A. G. Mikos, A Hari Reddi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The effects of poly(propylenefumarate-co-ethylene glycol) (P(PF-co-EG)) hydrogel encapsulation to repair damaged articular cartilage tissue, were investigated. The effects of P(PF-co-EG) and glycerol addition to culture media were observed for subsequent 4 hr of proteoglycan synthesis by freshly isolated chondrocytes cultured in monolayer on tissue culture polystyrene. When P(PF-co-EG) and glycerol were added to the media, proteoglycan synthesis was significantly higher than that in normal culture media. The results show that the components used in the formation of P(PF-co-EG) hydrogels allow the retention of the chondrocytic phenotype.

Original languageEnglish (US)
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages4
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: May 17 2004May 21 2004

Other

OtherTransactions - 7th World Biomaterials Congress
CountryAustralia
CitySydney
Period5/17/045/21/04

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Fisher, J. P., Jo, S., Mikos, A. G., & Reddi, A. H. (2004). Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering. In Transactions - 7th World Biomaterials Congress (pp. 4)