Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering

J. P. Fisher; S. Jo; A. G. Mikos; A Hari Reddi

Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering

J. P. Fisher, S. Jo, A. G. Mikos, A Hari Reddi

Orthopaedic Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

The effects of poly(propylenefumarate-co-ethylene glycol) (P(PF-co-EG)) hydrogel encapsulation to repair damaged articular cartilage tissue, were investigated. The effects of P(PF-co-EG) and glycerol addition to culture media were observed for subsequent 4 hr of proteoglycan synthesis by freshly isolated chondrocytes cultured in monolayer on tissue culture polystyrene. When P(PF-co-EG) and glycerol were added to the media, proteoglycan synthesis was significantly higher than that in normal culture media. The results show that the components used in the formation of P(PF-co-EG) hydrogels allow the retention of the chondrocytic phenotype.

Original language	English (US)
Title of host publication	Transactions - 7th World Biomaterials Congress
Pages	4
Number of pages	1
State	Published - 2004
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: May 17 2004 → May 21 2004

Other

Other	Transactions - 7th World Biomaterials Congress
Country	Australia
City	Sydney
Period	5/17/04 → 5/21/04

ASJC Scopus subject areas

Engineering(all)

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Cite this

@inproceedings{904058659405446eaadab0cf751fed4a,

title = "Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering",

abstract = "The effects of poly(propylenefumarate-co-ethylene glycol) (P(PF-co-EG)) hydrogel encapsulation to repair damaged articular cartilage tissue, were investigated. The effects of P(PF-co-EG) and glycerol addition to culture media were observed for subsequent 4 hr of proteoglycan synthesis by freshly isolated chondrocytes cultured in monolayer on tissue culture polystyrene. When P(PF-co-EG) and glycerol were added to the media, proteoglycan synthesis was significantly higher than that in normal culture media. The results show that the components used in the formation of P(PF-co-EG) hydrogels allow the retention of the chondrocytic phenotype.",

author = "Fisher, {J. P.} and S. Jo and Mikos, {A. G.} and Reddi, {A Hari}",

year = "2004",

language = "English (US)",

isbn = "1877040193",

pages = "4",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

}

TY - GEN

T1 - Thermoreversible hydrogel scaffolds for articular cartilage tissue engineering

AU - Fisher, J. P.

AU - Jo, S.

AU - Mikos, A. G.

AU - Reddi, A Hari

PY - 2004

Y1 - 2004

N2 - The effects of poly(propylenefumarate-co-ethylene glycol) (P(PF-co-EG)) hydrogel encapsulation to repair damaged articular cartilage tissue, were investigated. The effects of P(PF-co-EG) and glycerol addition to culture media were observed for subsequent 4 hr of proteoglycan synthesis by freshly isolated chondrocytes cultured in monolayer on tissue culture polystyrene. When P(PF-co-EG) and glycerol were added to the media, proteoglycan synthesis was significantly higher than that in normal culture media. The results show that the components used in the formation of P(PF-co-EG) hydrogels allow the retention of the chondrocytic phenotype.

AB - The effects of poly(propylenefumarate-co-ethylene glycol) (P(PF-co-EG)) hydrogel encapsulation to repair damaged articular cartilage tissue, were investigated. The effects of P(PF-co-EG) and glycerol addition to culture media were observed for subsequent 4 hr of proteoglycan synthesis by freshly isolated chondrocytes cultured in monolayer on tissue culture polystyrene. When P(PF-co-EG) and glycerol were added to the media, proteoglycan synthesis was significantly higher than that in normal culture media. The results show that the components used in the formation of P(PF-co-EG) hydrogels allow the retention of the chondrocytic phenotype.

UR - http://www.scopus.com/inward/record.url?scp=13844273356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844273356&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:13844273356

SN - 1877040193

SN - 9781877040191

SP - 4

BT - Transactions - 7th World Biomaterials Congress

T2 - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

ER -