Abstract
Shape memory polymer stent prototypes were fabricated from thermoplastic polyurethane. Commercial stents are generally made of stainless steel or other alloys. These alloys are too stiff and prevent most stent designs from being able to navigate small and tortuous vessels to reach intracranial lesions. A solid tubular model and a high flexibility laser etched model are presented. The stents were tested for collapse in a pressure chamber. At 37°C, the full collapse pressure was comparable to that of commercially available stents, and higher than the estimatedmaximumpressure exerted byintracranial arteries. However, there is a potential for onset of collapse, which needs further study. The stents were crimped and expanded, the laser-etched stent showed full recovery with an expansion ratio of 2.7 and a 1% axial shortening.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 421-429 |
| Number of pages | 9 |
| Journal | Journal of Biomedical Materials Research - Part B Applied Biomaterials |
| Volume | 90 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jul 2009 |
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Keywords
- In vitro
- Mechanical properties
- Polyurethane(s)
- Vascular stents
ASJC Scopus subject areas
- Biomedical Engineering
- Biomaterials
Cite this
Thermomechanical properties, collapse pressure, and expansion of shape memory polymer neurovascular stent prototypes. / Baer, Géraldine M.; Wilson, Thomas S.; Small IV, Ward; Hartman, Jonathan; Benett, William J.; Matthews, Dennis L; Maitland, Duncan J.
In: Journal of Biomedical Materials Research - Part B Applied Biomaterials, Vol. 90, No. 1, 07.2009, p. 421-429.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Thermomechanical properties, collapse pressure, and expansion of shape memory polymer neurovascular stent prototypes
AU - Baer, Géraldine M.
AU - Wilson, Thomas S.
AU - Small IV, Ward
AU - Hartman, Jonathan
AU - Benett, William J.
AU - Matthews, Dennis L
AU - Maitland, Duncan J.
PY - 2009/7
Y1 - 2009/7
N2 - Shape memory polymer stent prototypes were fabricated from thermoplastic polyurethane. Commercial stents are generally made of stainless steel or other alloys. These alloys are too stiff and prevent most stent designs from being able to navigate small and tortuous vessels to reach intracranial lesions. A solid tubular model and a high flexibility laser etched model are presented. The stents were tested for collapse in a pressure chamber. At 37°C, the full collapse pressure was comparable to that of commercially available stents, and higher than the estimatedmaximumpressure exerted byintracranial arteries. However, there is a potential for onset of collapse, which needs further study. The stents were crimped and expanded, the laser-etched stent showed full recovery with an expansion ratio of 2.7 and a 1% axial shortening.
AB - Shape memory polymer stent prototypes were fabricated from thermoplastic polyurethane. Commercial stents are generally made of stainless steel or other alloys. These alloys are too stiff and prevent most stent designs from being able to navigate small and tortuous vessels to reach intracranial lesions. A solid tubular model and a high flexibility laser etched model are presented. The stents were tested for collapse in a pressure chamber. At 37°C, the full collapse pressure was comparable to that of commercially available stents, and higher than the estimatedmaximumpressure exerted byintracranial arteries. However, there is a potential for onset of collapse, which needs further study. The stents were crimped and expanded, the laser-etched stent showed full recovery with an expansion ratio of 2.7 and a 1% axial shortening.
KW - In vitro
KW - Mechanical properties
KW - Polyurethane(s)
KW - Vascular stents
UR - http://www.scopus.com/inward/record.url?scp=67650812611&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67650812611&partnerID=8YFLogxK
U2 - 10.1002/jbm.b.31301
DO - 10.1002/jbm.b.31301
M3 - Article
C2 - 19107804
AN - SCOPUS:67650812611
VL - 90
SP - 421
EP - 429
JO - Journal of Biomedical Materials Research - Part A
JF - Journal of Biomedical Materials Research - Part A
SN - 1549-3296
IS - 1
ER -