Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera

Olga Baum, Sebastian Wachsmann-Hogiu, Emil Sobol

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.

Original languageEnglish (US)
Title of host publicationOptical Elastography and Tissue Biomechanics V
PublisherSPIE
Volume10496
ISBN (Electronic)9781510614772
DOIs
StatePublished - Jan 1 2018
EventOptical Elastography and Tissue Biomechanics V 2018 - San Francisco, United States
Duration: Jan 27 2018Jan 28 2018

Other

OtherOptical Elastography and Tissue Biomechanics V 2018
CountryUnited States
CitySan Francisco
Period1/27/181/28/18

Keywords

  • atomic force microscopy
  • gas nanobubbles
  • glaucoma
  • intraocular pressure
  • laser
  • Stabilization mechanism
  • super-resolution structured-illumination microscopy
  • thermo-mechanical stress

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Baum, O., Wachsmann-Hogiu, S., & Sobol, E. (2018). Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. In Optical Elastography and Tissue Biomechanics V (Vol. 10496). [1049617] SPIE. https://doi.org/10.1117/12.2289885