Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera

Olga Baum, Sebastian Wachsmann-Hogiu, Emil Sobol

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.

Original languageEnglish (US)
Title of host publicationOptical Elastography and Tissue Biomechanics V
PublisherSPIE
Volume10496
ISBN (Electronic)9781510614772
DOIs
StatePublished - Jan 1 2018
EventOptical Elastography and Tissue Biomechanics V 2018 - San Francisco, United States
Duration: Jan 27 2018Jan 28 2018

Other

OtherOptical Elastography and Tissue Biomechanics V 2018
CountryUnited States
CitySan Francisco
Period1/27/181/28/18

Fingerprint

Sclera
Pore structure
Lasers
Stabilization
stabilization
porosity
Gases
Laser radiation
lasers
intraocular pressure
gases
laser beams
glaucoma
healing
hydraulics
Gas Lasers
Radiation Effects
permeability
Intraocular Pressure
bubbles

Keywords

  • atomic force microscopy
  • gas nanobubbles
  • glaucoma
  • intraocular pressure
  • laser
  • Stabilization mechanism
  • super-resolution structured-illumination microscopy
  • thermo-mechanical stress

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Baum, O., Wachsmann-Hogiu, S., & Sobol, E. (2018). Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. In Optical Elastography and Tissue Biomechanics V (Vol. 10496). [1049617] SPIE. https://doi.org/10.1117/12.2289885

Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. / Baum, Olga; Wachsmann-Hogiu, Sebastian; Sobol, Emil.

Optical Elastography and Tissue Biomechanics V. Vol. 10496 SPIE, 2018. 1049617.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Baum, O, Wachsmann-Hogiu, S & Sobol, E 2018, Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. in Optical Elastography and Tissue Biomechanics V. vol. 10496, 1049617, SPIE, Optical Elastography and Tissue Biomechanics V 2018, San Francisco, United States, 1/27/18. https://doi.org/10.1117/12.2289885
Baum, Olga ; Wachsmann-Hogiu, Sebastian ; Sobol, Emil. / Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. Optical Elastography and Tissue Biomechanics V. Vol. 10496 SPIE, 2018.
@inproceedings{1127d0fba6844309b7e0a3a28dbe26b3,
title = "Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera",
abstract = "Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.",
keywords = "atomic force microscopy, gas nanobubbles, glaucoma, intraocular pressure, laser, Stabilization mechanism, super-resolution structured-illumination microscopy, thermo-mechanical stress",
author = "Olga Baum and Sebastian Wachsmann-Hogiu and Emil Sobol",
year = "2018",
month = "1",
day = "1",
doi = "10.1117/12.2289885",
language = "English (US)",
volume = "10496",
booktitle = "Optical Elastography and Tissue Biomechanics V",
publisher = "SPIE",

}

TY - GEN

T1 - Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera

AU - Baum, Olga

AU - Wachsmann-Hogiu, Sebastian

AU - Sobol, Emil

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.

AB - Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.

KW - atomic force microscopy

KW - gas nanobubbles

KW - glaucoma

KW - intraocular pressure

KW - laser

KW - Stabilization mechanism

KW - super-resolution structured-illumination microscopy

KW - thermo-mechanical stress

UR - http://www.scopus.com/inward/record.url?scp=85045154772&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85045154772&partnerID=8YFLogxK

U2 - 10.1117/12.2289885

DO - 10.1117/12.2289885

M3 - Conference contribution

AN - SCOPUS:85045154772

VL - 10496

BT - Optical Elastography and Tissue Biomechanics V

PB - SPIE

ER -