Abstract
Thermo-mechanical effect of laser radiation is a basis of new method of normalization of intraocular pressure in glaucomatous eyes due to laser-assisted pore formation in eye sclera. Laser-induced creation of pores in sclera increases hydraulic permeability. Stability of laser-induced pore system is achieved via gas nano-bubbles arisen in the sclera under laser radiation as a result of temperature dependency of gas solubility. The stabilization of laser-induced gas and pore systems in the tissue is an important mechanism for a long lasting healing of glaucoma observed in clinical trials with one year follow-up.
| Original language | English (US) |
|---|---|
| Title of host publication | Optical Elastography and Tissue Biomechanics V |
| Publisher | SPIE |
| Volume | 10496 |
| ISBN (Electronic) | 9781510614772 |
| DOIs | |
| State | Published - Jan 1 2018 |
| Event | Optical Elastography and Tissue Biomechanics V 2018 - San Francisco, United States Duration: Jan 27 2018 → Jan 28 2018 |
Other
| Other | Optical Elastography and Tissue Biomechanics V 2018 |
|---|---|
| Country | United States |
| City | San Francisco |
| Period | 1/27/18 → 1/28/18 |
Keywords
- atomic force microscopy
- gas nanobubbles
- glaucoma
- intraocular pressure
- laser
- Stabilization mechanism
- super-resolution structured-illumination microscopy
- thermo-mechanical stress
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Biomaterials
- Radiology Nuclear Medicine and imaging
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Cite this
Baum, O., Wachsmann-Hogiu, S., & Sobol, E. (2018). Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. In Optical Elastography and Tissue Biomechanics V (Vol. 10496). [1049617] SPIE. https://doi.org/10.1117/12.2289885