Abstract
Nb rat autonomous prostatic adenocarcinomas were transplanted into several groups of syngeneic Nb rats. Chemotherapy using 5-fluorouracil, methotrexate, adriamycin, and cyclophosphamide was evaluated. Significance was seen with the use of these agents with varying doses. Cyclophosphamide and 5-fluorouracil treated animals had complete tumor regression whereas adriamycin and methotrexate treated animals had cessation of tumor volume increase in some groups after chemotherapy; however, neither agent causes complete tumor regression.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 203-206 |
| Number of pages | 4 |
| Journal | Investigative Urology |
| Volume | 17 |
| Issue number | 3 |
| State | Published - 1979 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
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Drago, J. R., Goldman, L. B., Maurer, R. E., Gershwin, M. E., & Eckels, D. D. (1979). Therapeutic manipulation of Nb rat prostatic adenocarcinomas. Chemotherapeutic evaluation of autonomous tumors. Investigative Urology, 17(3), 203-206.