Nb rat autonomous prostatic adenocarcinomas were transplanted into several groups of syngeneic Nb rats. Chemotherapy using 5-fluorouracil, methotrexate, adriamycin, and cyclophosphamide was evaluated. Significance was seen with the use of these agents with varying doses. Cyclophosphamide and 5-fluorouracil treated animals had complete tumor regression whereas adriamycin and methotrexate treated animals had cessation of tumor volume increase in some groups after chemotherapy; however, neither agent causes complete tumor regression.
|Original language||English (US)|
|Number of pages||4|
|State||Published - 1979|
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