甲烷治疗疾病效应及其机制

Translated title of the contribution: Therapeutic effect of methane and its mechanism in disease treatment

Zhou heng Ye, Ke Ning, Bradley P. Ander, Xue jun Sun

Research output: Contribution to journalReview articlepeer-review

Abstract

Methane is the simplest hydrocarbon, consisting of one carbon atom and four hydrogen atoms. It is abundant in marsh gas, livestock rumination, and combustible ice. Little is known about the use of methane in human disease treatment. Current research indicates that methane is useful for treating several diseases including ischemia and reperfusion injury, and inflammatory diseases. The mechanisms underlying the protective effects of methane appear primarily to involve anti-oxidation, anti-inflammation, and anti-apoptosis. In this review, we describe the beneficial effects of methane on different diseases, summarize possible mechanisms by which methane may act in these conditions, and discuss the purpose of methane production in hypoxic conditions. Then we propose several promising directions for the future research.

Translated title of the contributionTherapeutic effect of methane and its mechanism in disease treatment
Original languageChinese
Pages (from-to)593-602
Number of pages10
JournalJournal of Zhejiang University: Science B
Volume21
Issue number8
DOIs
StatePublished - Aug 1 2020

Keywords

  • Inflammation
  • Ischemia and reperfusion injury
  • Methane treatment
  • Methanogenesis
  • R459.9

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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