Theoretical study of the contrast recovery and variance of MAP reconstructiions with applications to the selection of smoothing parameters

Jinyi Qi; Richard M. Leahy

Theoretical study of the contrast recovery and variance of MAP reconstructiions with applications to the selection of smoothing parameters

Jinyi Qi, Richard M. Leahy

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

We examine the spatial resolution and variance properties of PET images reconstructed using maximum a posteriori (MAP) or penalized-likelihood methods. Resolution is characterized by the contrast recovery coefficient (CRC) of the local impulse response. Simplified approximate expressions are derived for the local impulse response CRCs and variances for each voxel. Using these results we propose a practical scheme for selecting spatially variant smoothing parameters to optimize lesion detectability through maximization of the local CRC-to-noise ratio in the reconstructed image.

Original language	English (US)
Title of host publication	IEEE Nuclear Science Symposium and Medical Imaging Conference
Place of Publication	Piscataway, NJ, United States
Publisher	IEEE
Pages	2078-2085
Number of pages	8
Volume	3
ISBN (Print)	0780350227
State	Published - 1999
Externally published	Yes
Event	Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record - Toronto, Que, Can Duration: Nov 8 1998 → Nov 14 1998

Other

Other	Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record
City	Toronto, Que, Can
Period	11/8/98 → 11/14/98

ASJC Scopus subject areas

Computer Vision and Pattern Recognition
Industrial and Manufacturing Engineering

Cite this

Theoretical study of the contrast recovery and variance of MAP reconstructiions with applications to the selection of smoothing parameters. / Qi, Jinyi; Leahy, Richard M.

IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 3 Piscataway, NJ, United States : IEEE, 1999. p. 2078-2085.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Qi, J & Leahy, RM 1999, Theoretical study of the contrast recovery and variance of MAP reconstructiions with applications to the selection of smoothing parameters. in IEEE Nuclear Science Symposium and Medical Imaging Conference. vol. 3, IEEE, Piscataway, NJ, United States, pp. 2078-2085, Proceedings of the 1998 IEEE Nuclear Science Symposium Conference Record, Toronto, Que, Can, 11/8/98.

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AB - We examine the spatial resolution and variance properties of PET images reconstructed using maximum a posteriori (MAP) or penalized-likelihood methods. Resolution is characterized by the contrast recovery coefficient (CRC) of the local impulse response. Simplified approximate expressions are derived for the local impulse response CRCs and variances for each voxel. Using these results we propose a practical scheme for selecting spatially variant smoothing parameters to optimize lesion detectability through maximization of the local CRC-to-noise ratio in the reconstructed image.

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ER -

Theoretical study of the contrast recovery and variance of MAP reconstructiions with applications to the selection of smoothing parameters

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ASJC Scopus subject areas

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