The Yin-Yang Sign of Severe Mitral Regurgitation

Pankaj Malhotra, Jonathan Yap, Edris Aman, Jason H. Rogers

Research output: Contribution to journalArticlepeer-review


In select patients with severe, eccentric mitral regurgitation, we have observed that the regurgitant jet may entrain blood along the left atrial wall to produce a Chinese yin-yang symbol on color Doppler. This clinical imaging series demonstrates this unique phenomenon in an 81-year-old woman with symptomatic, severe, functional mitral regurgitation secondary to non-ischemic cardiomyopathy who was referred for transcatheter mitral valve repair. The yin-yang symbol resolved on transthoracic echocardiography after placement of 2 MitraClip NTR devices.

Original languageEnglish (US)
Pages (from-to)E314
JournalThe Journal of invasive cardiology
Issue number4
StatePublished - Apr 1 2021


  • cardiac imaging
  • MitraClip implantation
  • transthoracic echocardiogram

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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