The value of surgery for retroperitoneal sarcoma

Jeffrey A. Norton, Sepideh Gholami, Charlotte D. Jacobs, Daniel S. Kapp, Layla M. Parast

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Introduction. Retroperitoneal sarcomas are uncommon large malignant tumors. Methods. Forty-one consecutive patients with localized retroperitoneal sarcoma were retrospectively studied. Results. Median age was 58 years (range 20-91 years). Median tumor size was 17.5cm (range 4-41cm). Only 2 tumors were 5cm. Most were liposarcoma (44) and high-grade (59). 59 were stage 3 and the rest was stage 1. Median followup was 10 months (range 1-106 months). Thirty-eight patients had an initial complete resection; 15 (37) developed recurrent sarcoma and 12 (80) had a second complete resection. Patients with an initial complete resection had a 5-year survival of 46. For all patients, tumor grade affected overall survival (P=.006). Complete surgical resection improved overall survival for high-grade tumors (P=.03). Conclusions. Tumor grade/stage and complete surgical resection for high-grade tumors are important prognostic variables. Radiation therapy or chemotherapy had no significant impact on overall or recurrence-free survival. Complete surgical resection is the treatment of choice for patients with initial and locally recurrent retroperitoneal sarcoma.

Original languageEnglish (US)
Article number605840
StatePublished - Nov 17 2009
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging


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