The value of surgery for retroperitoneal sarcoma

Jeffrey A. Norton, Sepideh Gholami, Charlotte D. Jacobs, Daniel S. Kapp, Layla M. Parast

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Introduction. Retroperitoneal sarcomas are uncommon large malignant tumors. Methods. Forty-one consecutive patients with localized retroperitoneal sarcoma were retrospectively studied. Results. Median age was 58 years (range 20-91 years). Median tumor size was 17.5cm (range 4-41cm). Only 2 tumors were 5cm. Most were liposarcoma (44) and high-grade (59). 59 were stage 3 and the rest was stage 1. Median followup was 10 months (range 1-106 months). Thirty-eight patients had an initial complete resection; 15 (37) developed recurrent sarcoma and 12 (80) had a second complete resection. Patients with an initial complete resection had a 5-year survival of 46. For all patients, tumor grade affected overall survival (P=.006). Complete surgical resection improved overall survival for high-grade tumors (P=.03). Conclusions. Tumor grade/stage and complete surgical resection for high-grade tumors are important prognostic variables. Radiation therapy or chemotherapy had no significant impact on overall or recurrence-free survival. Complete surgical resection is the treatment of choice for patients with initial and locally recurrent retroperitoneal sarcoma.

Original languageEnglish (US)
Article number605840
JournalSarcoma
Volume2009
DOIs
StatePublished - Nov 17 2009
Externally publishedYes

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Sarcoma
Neoplasms
Survival
Liposarcoma
Radiotherapy
Recurrence
Drug Therapy

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging

Cite this

Norton, J. A., Gholami, S., Jacobs, C. D., Kapp, D. S., & Parast, L. M. (2009). The value of surgery for retroperitoneal sarcoma. Sarcoma, 2009, [605840]. https://doi.org/10.1155/2009/605840

The value of surgery for retroperitoneal sarcoma. / Norton, Jeffrey A.; Gholami, Sepideh; Jacobs, Charlotte D.; Kapp, Daniel S.; Parast, Layla M.

In: Sarcoma, Vol. 2009, 605840, 17.11.2009.

Research output: Contribution to journalArticle

Norton, JA, Gholami, S, Jacobs, CD, Kapp, DS & Parast, LM 2009, 'The value of surgery for retroperitoneal sarcoma', Sarcoma, vol. 2009, 605840. https://doi.org/10.1155/2009/605840
Norton JA, Gholami S, Jacobs CD, Kapp DS, Parast LM. The value of surgery for retroperitoneal sarcoma. Sarcoma. 2009 Nov 17;2009. 605840. https://doi.org/10.1155/2009/605840
Norton, Jeffrey A. ; Gholami, Sepideh ; Jacobs, Charlotte D. ; Kapp, Daniel S. ; Parast, Layla M. / The value of surgery for retroperitoneal sarcoma. In: Sarcoma. 2009 ; Vol. 2009.
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