The value of a risk model for early-onset candidemia

Christian E Sandrock, Javeed Siddiqui

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Bloodstream infections from Candida species are associated with an increased length of stay, increased hospital costs, and higher mortality when compared with bacterial bloodstream infections. Delayed or inappropriate therapy in candidemia leads to increased mortality, thus early recognition becomes paramount. With biomarkers showing promise, blood cultures still remain the gold standard but require 24 to 72 hours for growth. The reliance on epidemiologic risk factors for the initiation of empiric antifungal therapy therefore provides the best method for early appropriate therapy. Shorr and colleagues have devised a risk score to identify patients with early-onset candidemia as defined by positive blood cultures within 2 days of admission, thus allowing for the initiation of early appropriate antifungal therapy.

Original languageEnglish (US)
Article number1005
JournalCritical Care
Volume13
Issue number6
DOIs
StatePublished - Nov 18 2009

Fingerprint

Candidemia
Epidemiologic Factors
Mortality
Hospital Costs
Secondary Prevention
Candida
Bacterial Infections
Length of Stay
Therapeutics
Biomarkers
Growth
Infection
Blood Culture

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Medicine(all)

Cite this

The value of a risk model for early-onset candidemia. / Sandrock, Christian E; Siddiqui, Javeed.

In: Critical Care, Vol. 13, No. 6, 1005, 18.11.2009.

Research output: Contribution to journalArticle

@article{10467b8c71f94ec4ae9e261b60f985a5,
title = "The value of a risk model for early-onset candidemia",
abstract = "Bloodstream infections from Candida species are associated with an increased length of stay, increased hospital costs, and higher mortality when compared with bacterial bloodstream infections. Delayed or inappropriate therapy in candidemia leads to increased mortality, thus early recognition becomes paramount. With biomarkers showing promise, blood cultures still remain the gold standard but require 24 to 72 hours for growth. The reliance on epidemiologic risk factors for the initiation of empiric antifungal therapy therefore provides the best method for early appropriate therapy. Shorr and colleagues have devised a risk score to identify patients with early-onset candidemia as defined by positive blood cultures within 2 days of admission, thus allowing for the initiation of early appropriate antifungal therapy.",
author = "Sandrock, {Christian E} and Javeed Siddiqui",
year = "2009",
month = "11",
day = "18",
doi = "10.1186/cc8127",
language = "English (US)",
volume = "13",
journal = "Critical Care",
issn = "1364-8535",
publisher = "BioMed Central Ltd.",
number = "6",

}

TY - JOUR

T1 - The value of a risk model for early-onset candidemia

AU - Sandrock, Christian E

AU - Siddiqui, Javeed

PY - 2009/11/18

Y1 - 2009/11/18

N2 - Bloodstream infections from Candida species are associated with an increased length of stay, increased hospital costs, and higher mortality when compared with bacterial bloodstream infections. Delayed or inappropriate therapy in candidemia leads to increased mortality, thus early recognition becomes paramount. With biomarkers showing promise, blood cultures still remain the gold standard but require 24 to 72 hours for growth. The reliance on epidemiologic risk factors for the initiation of empiric antifungal therapy therefore provides the best method for early appropriate therapy. Shorr and colleagues have devised a risk score to identify patients with early-onset candidemia as defined by positive blood cultures within 2 days of admission, thus allowing for the initiation of early appropriate antifungal therapy.

AB - Bloodstream infections from Candida species are associated with an increased length of stay, increased hospital costs, and higher mortality when compared with bacterial bloodstream infections. Delayed or inappropriate therapy in candidemia leads to increased mortality, thus early recognition becomes paramount. With biomarkers showing promise, blood cultures still remain the gold standard but require 24 to 72 hours for growth. The reliance on epidemiologic risk factors for the initiation of empiric antifungal therapy therefore provides the best method for early appropriate therapy. Shorr and colleagues have devised a risk score to identify patients with early-onset candidemia as defined by positive blood cultures within 2 days of admission, thus allowing for the initiation of early appropriate antifungal therapy.

UR - http://www.scopus.com/inward/record.url?scp=77951624641&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951624641&partnerID=8YFLogxK

U2 - 10.1186/cc8127

DO - 10.1186/cc8127

M3 - Article

C2 - 19939291

AN - SCOPUS:77951624641

VL - 13

JO - Critical Care

JF - Critical Care

SN - 1364-8535

IS - 6

M1 - 1005

ER -