The utility of transcriptomics in fish conservation

Richard E Connon, Ken M. Jeffries, Lisa M. Komoroske, Anne E. Todgham, Nann A. Fangue

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

There is growing recognition of the need to understand the mechanisms underlying organismal resilience (i.e. tolerance, acclimatization) to environmental change to support the conservation management of sensitive and economically important species. Here, we discuss how functional genomics can be used in conservation biology to provide a cellular-level understanding of organismal responses to environmental conditions. In particular, the integration of transcriptomics with physiological and ecological research is increasingly playing an important role in identifying functional physiological thresholds predictive of compensatory responses and detrimental outcomes, transforming the way we can study issues in conservation biology. Notably, with technological advances in RNA sequencing, transcriptome-wide approaches can now be applied to species where no prior genomic sequence information is available to develop species-specific tools and investigate sublethal impacts that can contribute to population declines over generations and undermine prospects for long-term conservation success. Here, we examine the use of transcriptomics as a means of determining organismal responses to environmental stressors and use key study examples of conservation concern in fishes to highlight the added value of transcriptome-wide data to the identification of functional response pathways. Finally, we discuss the gaps between the core science and policy frameworks and how thresholds identified through transcriptomic evaluations provide evidence that can be more readily used by resource managers.

Original languageEnglish (US)
JournalJournal of Experimental Biology
Volume221
Issue number2
DOIs
StatePublished - Jan 1 2018

Fingerprint

transcriptomics
Transcriptome
Fishes
RNA Sequence Analysis
transcriptome
Acclimatization
fish
Genomics
genomics
Biological Sciences
value added
functional response
acclimation
managers
conservation management
population decline
sequence analysis
Research
Population
RNA

Keywords

  • Conservation physiology
  • Endangered species
  • Molecular approaches

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Physiology
  • Aquatic Science
  • Animal Science and Zoology
  • Molecular Biology
  • Insect Science

Cite this

Connon, R. E., Jeffries, K. M., Komoroske, L. M., Todgham, A. E., & Fangue, N. A. (2018). The utility of transcriptomics in fish conservation. Journal of Experimental Biology, 221(2). https://doi.org/10.1242/jeb.148833

The utility of transcriptomics in fish conservation. / Connon, Richard E; Jeffries, Ken M.; Komoroske, Lisa M.; Todgham, Anne E.; Fangue, Nann A.

In: Journal of Experimental Biology, Vol. 221, No. 2, 01.01.2018.

Research output: Contribution to journalReview article

Connon, RE, Jeffries, KM, Komoroske, LM, Todgham, AE & Fangue, NA 2018, 'The utility of transcriptomics in fish conservation', Journal of Experimental Biology, vol. 221, no. 2. https://doi.org/10.1242/jeb.148833
Connon, Richard E ; Jeffries, Ken M. ; Komoroske, Lisa M. ; Todgham, Anne E. ; Fangue, Nann A. / The utility of transcriptomics in fish conservation. In: Journal of Experimental Biology. 2018 ; Vol. 221, No. 2.
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