The use of transvaginal ultrasound in Type II endometrial cancer

Caroline C. Billingsley, Kimberly A. Kenne, Catherine D Cansino, Floor J. Backes, David E. Cohn, David M. O'Malley, Larry J. Copeland, Jeffrey M. Fowler, Ritu Salani

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Objective To determine the use of the transvaginal ultrasound (TVUS) in postmenopausal women with type II endometrial cancer. Methods/Materials A retrospective review was conducted for 173 women with pathology proven type II endometrial cancer at a single institution. Those who underwent preoperative TVUS were included, and the following data were obtained: endometrial stripe (EMS) measurement, uterine and/or adnexal findings, and uterine size/volume. Clinicopathologic factors were abstracted. Descriptive and regression analyses were performed. Results Fifty-eight women comprised the cohort, and the median age was 66.5 years (50-85 years). The most commonly reported symptom was postmenopausal bleeding in 53 patients (91.4%). The EMS was reported as thin (≤5mm) or indistinct in 16 patients (27.5%). Approximately 60% of patients had 1 or more ultrasound abnormalities: intracavitary mass (31%), intracavitary fluid (12.1%), myometrial lesion (31.03%), and adnexal mass (12.1%). Poorly differentiated endometrioid cancer (53.45%) represented the predominant histology. Of the 16 (27.5%) women with a thin/indistinct EMS, 5 women (8.6%) did not have any abnormal ultrasound findings whatsoever. Conclusions Women with type II endometrial cancer had a thin/indistinct EMS on TVUS in approximately 25% of cases. Lack of any ultrasound abnormality, including a thickened EMS, was noted in approximately 10% of patients. The use of TVUS, which has been of value in type I cancer, is limited in type II endometrial cancer. Therefore, endometrial sampling should be included in the evaluation of all women with postmenopausal bleeding, regardless of EMS thickness.

Original languageEnglish (US)
Pages (from-to)858-862
Number of pages5
JournalInternational Journal of Gynecological Cancer
Volume25
Issue number5
DOIs
StatePublished - Jun 4 2015

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Endometrial Neoplasms
Hemorrhage
Neoplasms
Histology
Regression Analysis
Pathology

Keywords

  • Endometrial cancer
  • Endometrial stripe
  • Type II, Pelvic ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology

Cite this

Billingsley, C. C., Kenne, K. A., Cansino, C. D., Backes, F. J., Cohn, D. E., O'Malley, D. M., ... Salani, R. (2015). The use of transvaginal ultrasound in Type II endometrial cancer. International Journal of Gynecological Cancer, 25(5), 858-862. https://doi.org/10.1097/IGC.0000000000000423

The use of transvaginal ultrasound in Type II endometrial cancer. / Billingsley, Caroline C.; Kenne, Kimberly A.; Cansino, Catherine D; Backes, Floor J.; Cohn, David E.; O'Malley, David M.; Copeland, Larry J.; Fowler, Jeffrey M.; Salani, Ritu.

In: International Journal of Gynecological Cancer, Vol. 25, No. 5, 04.06.2015, p. 858-862.

Research output: Contribution to journalArticle

Billingsley, CC, Kenne, KA, Cansino, CD, Backes, FJ, Cohn, DE, O'Malley, DM, Copeland, LJ, Fowler, JM & Salani, R 2015, 'The use of transvaginal ultrasound in Type II endometrial cancer', International Journal of Gynecological Cancer, vol. 25, no. 5, pp. 858-862. https://doi.org/10.1097/IGC.0000000000000423
Billingsley, Caroline C. ; Kenne, Kimberly A. ; Cansino, Catherine D ; Backes, Floor J. ; Cohn, David E. ; O'Malley, David M. ; Copeland, Larry J. ; Fowler, Jeffrey M. ; Salani, Ritu. / The use of transvaginal ultrasound in Type II endometrial cancer. In: International Journal of Gynecological Cancer. 2015 ; Vol. 25, No. 5. pp. 858-862.
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abstract = "Objective To determine the use of the transvaginal ultrasound (TVUS) in postmenopausal women with type II endometrial cancer. Methods/Materials A retrospective review was conducted for 173 women with pathology proven type II endometrial cancer at a single institution. Those who underwent preoperative TVUS were included, and the following data were obtained: endometrial stripe (EMS) measurement, uterine and/or adnexal findings, and uterine size/volume. Clinicopathologic factors were abstracted. Descriptive and regression analyses were performed. Results Fifty-eight women comprised the cohort, and the median age was 66.5 years (50-85 years). The most commonly reported symptom was postmenopausal bleeding in 53 patients (91.4{\%}). The EMS was reported as thin (≤5mm) or indistinct in 16 patients (27.5{\%}). Approximately 60{\%} of patients had 1 or more ultrasound abnormalities: intracavitary mass (31{\%}), intracavitary fluid (12.1{\%}), myometrial lesion (31.03{\%}), and adnexal mass (12.1{\%}). Poorly differentiated endometrioid cancer (53.45{\%}) represented the predominant histology. Of the 16 (27.5{\%}) women with a thin/indistinct EMS, 5 women (8.6{\%}) did not have any abnormal ultrasound findings whatsoever. Conclusions Women with type II endometrial cancer had a thin/indistinct EMS on TVUS in approximately 25{\%} of cases. Lack of any ultrasound abnormality, including a thickened EMS, was noted in approximately 10{\%} of patients. The use of TVUS, which has been of value in type I cancer, is limited in type II endometrial cancer. Therefore, endometrial sampling should be included in the evaluation of all women with postmenopausal bleeding, regardless of EMS thickness.",
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AU - O'Malley, David M.

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AU - Salani, Ritu

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N2 - Objective To determine the use of the transvaginal ultrasound (TVUS) in postmenopausal women with type II endometrial cancer. Methods/Materials A retrospective review was conducted for 173 women with pathology proven type II endometrial cancer at a single institution. Those who underwent preoperative TVUS were included, and the following data were obtained: endometrial stripe (EMS) measurement, uterine and/or adnexal findings, and uterine size/volume. Clinicopathologic factors were abstracted. Descriptive and regression analyses were performed. Results Fifty-eight women comprised the cohort, and the median age was 66.5 years (50-85 years). The most commonly reported symptom was postmenopausal bleeding in 53 patients (91.4%). The EMS was reported as thin (≤5mm) or indistinct in 16 patients (27.5%). Approximately 60% of patients had 1 or more ultrasound abnormalities: intracavitary mass (31%), intracavitary fluid (12.1%), myometrial lesion (31.03%), and adnexal mass (12.1%). Poorly differentiated endometrioid cancer (53.45%) represented the predominant histology. Of the 16 (27.5%) women with a thin/indistinct EMS, 5 women (8.6%) did not have any abnormal ultrasound findings whatsoever. Conclusions Women with type II endometrial cancer had a thin/indistinct EMS on TVUS in approximately 25% of cases. Lack of any ultrasound abnormality, including a thickened EMS, was noted in approximately 10% of patients. The use of TVUS, which has been of value in type I cancer, is limited in type II endometrial cancer. Therefore, endometrial sampling should be included in the evaluation of all women with postmenopausal bleeding, regardless of EMS thickness.

AB - Objective To determine the use of the transvaginal ultrasound (TVUS) in postmenopausal women with type II endometrial cancer. Methods/Materials A retrospective review was conducted for 173 women with pathology proven type II endometrial cancer at a single institution. Those who underwent preoperative TVUS were included, and the following data were obtained: endometrial stripe (EMS) measurement, uterine and/or adnexal findings, and uterine size/volume. Clinicopathologic factors were abstracted. Descriptive and regression analyses were performed. Results Fifty-eight women comprised the cohort, and the median age was 66.5 years (50-85 years). The most commonly reported symptom was postmenopausal bleeding in 53 patients (91.4%). The EMS was reported as thin (≤5mm) or indistinct in 16 patients (27.5%). Approximately 60% of patients had 1 or more ultrasound abnormalities: intracavitary mass (31%), intracavitary fluid (12.1%), myometrial lesion (31.03%), and adnexal mass (12.1%). Poorly differentiated endometrioid cancer (53.45%) represented the predominant histology. Of the 16 (27.5%) women with a thin/indistinct EMS, 5 women (8.6%) did not have any abnormal ultrasound findings whatsoever. Conclusions Women with type II endometrial cancer had a thin/indistinct EMS on TVUS in approximately 25% of cases. Lack of any ultrasound abnormality, including a thickened EMS, was noted in approximately 10% of patients. The use of TVUS, which has been of value in type I cancer, is limited in type II endometrial cancer. Therefore, endometrial sampling should be included in the evaluation of all women with postmenopausal bleeding, regardless of EMS thickness.

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