The use of transvaginal ultrasound in Type II endometrial cancer

Caroline C. Billingsley, Kimberly A. Kenne, Catherine D Cansino, Floor J. Backes, David E. Cohn, David M. O'Malley, Larry J. Copeland, Jeffrey M. Fowler, Ritu Salani

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Objective To determine the use of the transvaginal ultrasound (TVUS) in postmenopausal women with type II endometrial cancer. Methods/Materials A retrospective review was conducted for 173 women with pathology proven type II endometrial cancer at a single institution. Those who underwent preoperative TVUS were included, and the following data were obtained: endometrial stripe (EMS) measurement, uterine and/or adnexal findings, and uterine size/volume. Clinicopathologic factors were abstracted. Descriptive and regression analyses were performed. Results Fifty-eight women comprised the cohort, and the median age was 66.5 years (50-85 years). The most commonly reported symptom was postmenopausal bleeding in 53 patients (91.4%). The EMS was reported as thin (≤5mm) or indistinct in 16 patients (27.5%). Approximately 60% of patients had 1 or more ultrasound abnormalities: intracavitary mass (31%), intracavitary fluid (12.1%), myometrial lesion (31.03%), and adnexal mass (12.1%). Poorly differentiated endometrioid cancer (53.45%) represented the predominant histology. Of the 16 (27.5%) women with a thin/indistinct EMS, 5 women (8.6%) did not have any abnormal ultrasound findings whatsoever. Conclusions Women with type II endometrial cancer had a thin/indistinct EMS on TVUS in approximately 25% of cases. Lack of any ultrasound abnormality, including a thickened EMS, was noted in approximately 10% of patients. The use of TVUS, which has been of value in type I cancer, is limited in type II endometrial cancer. Therefore, endometrial sampling should be included in the evaluation of all women with postmenopausal bleeding, regardless of EMS thickness.

Original languageEnglish (US)
Pages (from-to)858-862
Number of pages5
JournalInternational Journal of Gynecological Cancer
Issue number5
StatePublished - Jun 4 2015


  • Endometrial cancer
  • Endometrial stripe
  • Type II, Pelvic ultrasound

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Oncology


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