The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles

Manisha Notay, Suzana Saric-Bosanac, Alexandra R. Vaughn, Simran Dhaliwal, Megha Trivedi, Paloma N. Reiter, Iryna Rybak, Connie C. Li, Larry B. Weiss, Lauren Ambrogio, Waqas Burney, Raja K Sivamani

Research output: Contribution to journalArticle

Abstract

Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose of this study was to assess whether there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha, a topical probiotic. Methods: In this prospective study, high-resolution photographs were obtained in twenty-nine participants at baseline and after using topical Nitrosomonas eutropha for seven days. Results: There was a significant difference in wrinkle depth and severity in the high concentration probiotic group. There was also a statistically significant improvement in pigmentation of the forehead and glabella in the higher concentration group. Conclusions: Nitrosomonas eutropha may have aesthetic benefits in terms of reducing the appearance of wrinkles. Larger studies with longer treatment and follow-up periods are required.

Original languageEnglish (US)
JournalJournal of Cosmetic Dermatology
DOIs
StatePublished - Jan 1 2019

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Nitrosomonas
Probiotics
Cosmetics
Forehead
Pigmentation
Esthetics
Ammonia
Prospective Studies
Bacteria

Keywords

  • photography
  • pigmentation
  • probiotics
  • wrinkles

ASJC Scopus subject areas

  • Dermatology

Cite this

The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles. / Notay, Manisha; Saric-Bosanac, Suzana; Vaughn, Alexandra R.; Dhaliwal, Simran; Trivedi, Megha; Reiter, Paloma N.; Rybak, Iryna; Li, Connie C.; Weiss, Larry B.; Ambrogio, Lauren; Burney, Waqas; Sivamani, Raja K.

In: Journal of Cosmetic Dermatology, 01.01.2019.

Research output: Contribution to journalArticle

Notay, M, Saric-Bosanac, S, Vaughn, AR, Dhaliwal, S, Trivedi, M, Reiter, PN, Rybak, I, Li, CC, Weiss, LB, Ambrogio, L, Burney, W & Sivamani, RK 2019, 'The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles', Journal of Cosmetic Dermatology. https://doi.org/10.1111/jocd.13060
Notay, Manisha ; Saric-Bosanac, Suzana ; Vaughn, Alexandra R. ; Dhaliwal, Simran ; Trivedi, Megha ; Reiter, Paloma N. ; Rybak, Iryna ; Li, Connie C. ; Weiss, Larry B. ; Ambrogio, Lauren ; Burney, Waqas ; Sivamani, Raja K. / The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles. In: Journal of Cosmetic Dermatology. 2019.
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abstract = "Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose of this study was to assess whether there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha, a topical probiotic. Methods: In this prospective study, high-resolution photographs were obtained in twenty-nine participants at baseline and after using topical Nitrosomonas eutropha for seven days. Results: There was a significant difference in wrinkle depth and severity in the high concentration probiotic group. There was also a statistically significant improvement in pigmentation of the forehead and glabella in the higher concentration group. Conclusions: Nitrosomonas eutropha may have aesthetic benefits in terms of reducing the appearance of wrinkles. Larger studies with longer treatment and follow-up periods are required.",
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