Abstract
Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose of this study was to assess whether there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha, a topical probiotic. Methods: In this prospective study, high-resolution photographs were obtained in twenty-nine participants at baseline and after using topical Nitrosomonas eutropha for seven days. Results: There was a significant difference in wrinkle depth and severity in the high concentration probiotic group. There was also a statistically significant improvement in pigmentation of the forehead and glabella in the higher concentration group. Conclusions: Nitrosomonas eutropha may have aesthetic benefits in terms of reducing the appearance of wrinkles. Larger studies with longer treatment and follow-up periods are required.
| Original language | English (US) |
|---|---|
| Journal | Journal of Cosmetic Dermatology |
| DOIs | |
| State | Published - Jan 1 2019 |
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Keywords
- photography
- pigmentation
- probiotics
- wrinkles
ASJC Scopus subject areas
- Dermatology
Cite this
The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles. / Notay, Manisha; Saric-Bosanac, Suzana; Vaughn, Alexandra R.; Dhaliwal, Simran; Trivedi, Megha; Reiter, Paloma N.; Rybak, Iryna; Li, Connie C.; Weiss, Larry B.; Ambrogio, Lauren; Burney, Waqas; Sivamani, Raja K.
In: Journal of Cosmetic Dermatology, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The use of topical Nitrosomonas eutropha for cosmetic improvement of facial wrinkles
AU - Notay, Manisha
AU - Saric-Bosanac, Suzana
AU - Vaughn, Alexandra R.
AU - Dhaliwal, Simran
AU - Trivedi, Megha
AU - Reiter, Paloma N.
AU - Rybak, Iryna
AU - Li, Connie C.
AU - Weiss, Larry B.
AU - Ambrogio, Lauren
AU - Burney, Waqas
AU - Sivamani, Raja K
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose of this study was to assess whether there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha, a topical probiotic. Methods: In this prospective study, high-resolution photographs were obtained in twenty-nine participants at baseline and after using topical Nitrosomonas eutropha for seven days. Results: There was a significant difference in wrinkle depth and severity in the high concentration probiotic group. There was also a statistically significant improvement in pigmentation of the forehead and glabella in the higher concentration group. Conclusions: Nitrosomonas eutropha may have aesthetic benefits in terms of reducing the appearance of wrinkles. Larger studies with longer treatment and follow-up periods are required.
AB - Background: Both topical and oral probiotics are becoming widely used. There is increasing interest in the cosmetic potential in topical probiotics. Nitrosomonas eutropha is an ammonia-oxidizing bacteria. Aim: The purpose of this study was to assess whether there is any improvement in facial wrinkles with the use of Nitrosomonas eutropha, a topical probiotic. Methods: In this prospective study, high-resolution photographs were obtained in twenty-nine participants at baseline and after using topical Nitrosomonas eutropha for seven days. Results: There was a significant difference in wrinkle depth and severity in the high concentration probiotic group. There was also a statistically significant improvement in pigmentation of the forehead and glabella in the higher concentration group. Conclusions: Nitrosomonas eutropha may have aesthetic benefits in terms of reducing the appearance of wrinkles. Larger studies with longer treatment and follow-up periods are required.
KW - photography
KW - pigmentation
KW - probiotics
KW - wrinkles
UR - http://www.scopus.com/inward/record.url?scp=85068390010&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85068390010&partnerID=8YFLogxK
U2 - 10.1111/jocd.13060
DO - 10.1111/jocd.13060
M3 - Article
AN - SCOPUS:85068390010
JO - Journal of Cosmetic Dermatology
JF - Journal of Cosmetic Dermatology
SN - 1473-2130
ER -