Using a system of random selection in patients with severe obstetric gynecologic infections, parenteral penicillin kanamycin was given to 23 women and clindamycin kanamycin was given to 21. Therapeutic response to the two antibiotic regimens was similar; no significant differences were noted in either the posttreatment fever index or the numbers of women requiring other therapy. There was a failure of response to the penicillin kanamycin regimen in those women with Bacteroides fragilis infection and to the clindamycin kanamycin regimen in some of the women with an Enterococcus infection. The implications of these findings for the future selection of antibiotics for patients with severe obstetric gynecologic infections are discussed.
|Original language||English (US)|
|Number of pages||8|
|Journal||Obstetrics and Gynecology|
|State||Published - 1974|
ASJC Scopus subject areas
- Obstetrics and Gynecology