The use of parenteral clindamycin in the treatment of obstetric gynecologic patients with severe infections. A comparison of a clindamycin kanamycin combination with penicillin kanamycin

W. J. Ledger, T. J. Kriewall, Richard L Sweet, F. R. Fekety

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Using a system of random selection in patients with severe obstetric gynecologic infections, parenteral penicillin kanamycin was given to 23 women and clindamycin kanamycin was given to 21. Therapeutic response to the two antibiotic regimens was similar; no significant differences were noted in either the posttreatment fever index or the numbers of women requiring other therapy. There was a failure of response to the penicillin kanamycin regimen in those women with Bacteroides fragilis infection and to the clindamycin kanamycin regimen in some of the women with an Enterococcus infection. The implications of these findings for the future selection of antibiotics for patients with severe obstetric gynecologic infections are discussed.

Original languageEnglish (US)
Pages (from-to)490-497
Number of pages8
JournalObstetrics and Gynecology
Volume43
Issue number4
StatePublished - 1974
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'The use of parenteral clindamycin in the treatment of obstetric gynecologic patients with severe infections. A comparison of a clindamycin kanamycin combination with penicillin kanamycin'. Together they form a unique fingerprint.

  • Cite this