Abstract
Using a system of random selection in patients with severe obstetric gynecologic infections, parenteral penicillin kanamycin was given to 23 women and clindamycin kanamycin was given to 21. Therapeutic response to the two antibiotic regimens was similar; no significant differences were noted in either the posttreatment fever index or the numbers of women requiring other therapy. There was a failure of response to the penicillin kanamycin regimen in those women with Bacteroides fragilis infection and to the clindamycin kanamycin regimen in some of the women with an Enterococcus infection. The implications of these findings for the future selection of antibiotics for patients with severe obstetric gynecologic infections are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 490-497 |
| Number of pages | 8 |
| Journal | Obstetrics and Gynecology |
| Volume | 43 |
| Issue number | 4 |
| State | Published - 1974 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Obstetrics and Gynecology
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The use of parenteral clindamycin in the treatment of obstetric gynecologic patients with severe infections. A comparison of a clindamycin kanamycin combination with penicillin kanamycin. / Ledger, W. J.; Kriewall, T. J.; Sweet, Richard L; Fekety, F. R.
In: Obstetrics and Gynecology, Vol. 43, No. 4, 1974, p. 490-497.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The use of parenteral clindamycin in the treatment of obstetric gynecologic patients with severe infections. A comparison of a clindamycin kanamycin combination with penicillin kanamycin
AU - Ledger, W. J.
AU - Kriewall, T. J.
AU - Sweet, Richard L
AU - Fekety, F. R.
PY - 1974
Y1 - 1974
N2 - Using a system of random selection in patients with severe obstetric gynecologic infections, parenteral penicillin kanamycin was given to 23 women and clindamycin kanamycin was given to 21. Therapeutic response to the two antibiotic regimens was similar; no significant differences were noted in either the posttreatment fever index or the numbers of women requiring other therapy. There was a failure of response to the penicillin kanamycin regimen in those women with Bacteroides fragilis infection and to the clindamycin kanamycin regimen in some of the women with an Enterococcus infection. The implications of these findings for the future selection of antibiotics for patients with severe obstetric gynecologic infections are discussed.
AB - Using a system of random selection in patients with severe obstetric gynecologic infections, parenteral penicillin kanamycin was given to 23 women and clindamycin kanamycin was given to 21. Therapeutic response to the two antibiotic regimens was similar; no significant differences were noted in either the posttreatment fever index or the numbers of women requiring other therapy. There was a failure of response to the penicillin kanamycin regimen in those women with Bacteroides fragilis infection and to the clindamycin kanamycin regimen in some of the women with an Enterococcus infection. The implications of these findings for the future selection of antibiotics for patients with severe obstetric gynecologic infections are discussed.
UR - http://www.scopus.com/inward/record.url?scp=0015965331&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015965331&partnerID=8YFLogxK
M3 - Article
C2 - 4593619
AN - SCOPUS:0015965331
VL - 43
SP - 490
EP - 497
JO - Obstetrics and Gynecology
JF - Obstetrics and Gynecology
SN - 0029-7844
IS - 4
ER -