The use of high-frequency oscillatory ventilation (HFOV) and extracorporeal membrane oxygenation (ECMO) in the management of the term/near term infant with respiratory failure

R. deLemos, B. Yoder, D. McCurnin, J. Kinsella, R. Clark, Donald Null

Research output: Contribution to journalArticle

31 Scopus citations


The use of high-frequency oscillatory ventilation (HFOV) was evaluated as a rescue intervention in 122 consecutive infants meeting criteria for extracorporeal membrane oxygenation (ECMO). Fifty-three percent responded to HFOV and never required ECMO, 3 65 died. Infants who ultimately required ECMO had lower aortic and pulmonary peak flow velocities, and lower pulmonary acceleration, circumferential fiber shortening and shortening fraction than those who were successfully managed with HFOV. The use of HFOV with an appropriate strategy decreased the need for ECMO in this patient population.

Original languageEnglish (US)
Pages (from-to)299-303
Number of pages5
JournalEarly Human Development
Issue number1-3
StatePublished - Jan 1 1992
Externally publishedYes



  • extracorporeal membrane oxygenation (ECMO)
  • high-frequency ventilation
  • respiratory failure
  • ventilation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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