The use of fMRI for determining the topographic organization of cortical fields in human and nonhuman primates

Elizabeth Disbrow, Timothy P L Roberts, Daniel Slutsky, Leah Krubitzer

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

In this study, we demonstrate activation of somatosensory cortex in the anesthetized macaque monkey and awake human using fMRI, and confirm the topographic organization of somatosensory cortex previously described in both species. The macaque model provides an efficient means of addressing questions regarding the capabilities and neurophysiological relevance of fMRI, and serves as an interface between established invasive electrophysiological methods in nonhuman primates, and noninvasive imaging assays of functional activation in humans.

Original languageEnglish (US)
Pages (from-to)167-173
Number of pages7
JournalBrain Research
Volume829
Issue number1-2
DOIs
StatePublished - May 22 1999

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Keywords

  • Anesthesia
  • Functional magnetic resonance imaging
  • Macaque
  • Somatosensory cortex
  • Topography

ASJC Scopus subject areas

  • Neuroscience(all)

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