The use of a urinary estrone conjugates assay for detection of optimal mating time in the cynomolgus macaque (Macaca fascicularis).

E. Behboodi, D. F. Katz, S. J. Samuels, Lisa A Tell, Andrew G Hendrickx, B. L. Lasley

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

Forty-four female cynomolgus macaques (Macaca fascicularis) were examined to determine the optimum fertile period for mating. Daily urinary estrone conjugates (E1C) were measured, beginning on day 7 of the menstrual cycle, until a 1.5-gold E1C rise above the baseline was detected. The females were bred the next morning. Pregnancies were verified in all animals at day 18 postbreeding, and/or on day 25 postbreeding. Serum progesterone levels were used to correlate the relationship between ovulation and the E1C peak. Forty-four of the 57 cycles indicated a urinary E1C peak between days 10-15 of the menstrual cycle; this peak occurred on the day following the initial 1.5-fold to twofold rise in 90% of the cycles. A single 2-hr mating period the day before, the day of, or the day after the E1C peak resulted in conception in 17 of 44 (38.6%) animals.

Original languageEnglish (US)
Pages (from-to)229-234
Number of pages6
JournalJournal of Medical Primatology
Volume20
Issue number5
StatePublished - Jul 1991

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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