The tissue is the issue: Personalized medicine for non-small cell lung cancer

Fred R. Hirsch, Murry W. Wynes, David R Gandara, Paul A. Bunn

Research output: Contribution to journalArticle

59 Scopus citations

Abstract

The development of molecular markers is crucial for improving therapy in advanced non-small cell lung cancer (NSCLC). Here, we review perspectives of biomarker-driven personalized therapy in NSCLC, with particular reference to the detection of EML4-ALK gene rearrangements. Different molecular assays, validation, and clinical application to different types of tissue specimens are discussed.

Original languageEnglish (US)
Pages (from-to)4909-4911
Number of pages3
JournalClinical Cancer Research
Volume16
Issue number20
DOIs
StatePublished - Oct 15 2010

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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