The temporomandibular joint of California sea lions (Zalophus californianus): Part 1 - Characterisation in health and disease

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objectives This study aimed to characterise the histologic, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of California sea lions. In addition, we sought to identify structure-function relationships and to characterise TMJ lesions found in this species.

Design Temporomandibular joints from fresh cadaver heads (n = 14) of California sea lions acquired from strandings were examined macroscopically and microscopically. The specimens were also evaluated for their mechanical and biochemical properties. Furthermore, if TMJ arthritic changes were present, joint characteristics were described and compared to healthy joints.

Results Five male and 9 female specimens demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs in the TMJ. Out of the 9 female specimens, 4 specimens had TMJ lesions were seen either in the articular surface or the disc. Histologically, these pathologic specimens demonstrated subchondral bone defects, cartilage irregularities and inflammatory cell infiltrates. The normal TMJ discs did not exhibit significant direction dependence in tensile stiffness or strength in the rostrocaudal direction compared with the mediolateral direction among normal discs or discs from affected joints. The TMJ discs were not found to be anisotropic in tensile properties. This feature was further supported by randomly oriented collagen fibres as seen by electron microscopy. Furthermore, no significant differences were detected in biochemical composition of the discs dependent upon population.

Conclusion The TMJ and its disc of the California sea lion exhibit similarities but also differences compared to other mammals with regards to structure-function relationships. A fibrous TMJ disc rich in collagen with minimal glycosaminoglycan content was characterised, and random fibre organisation was associated with isotropic mechanical properties in the central region of the disc.

Original languageEnglish (US)
Pages (from-to)208-215
Number of pages8
JournalArchives of Oral Biology
Volume60
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Sea Lions
Temporomandibular Joint Disc
Temporomandibular Joint
Joints
Health
Collagen
Glycosaminoglycans
Cadaver
Arthritis
Cartilage
Mammals
Electron Microscopy
Head
Bone and Bones
Population
Direction compound

Keywords

  • California sea lion
  • Cartilage
  • Osteoarthritis
  • Temporomandibular joint
  • Zalophus californianus

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Cell Biology
  • Dentistry(all)

Cite this

@article{7113f383414547db8da38997e0d6b782,
title = "The temporomandibular joint of California sea lions (Zalophus californianus): Part 1 - Characterisation in health and disease",
abstract = "Objectives This study aimed to characterise the histologic, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of California sea lions. In addition, we sought to identify structure-function relationships and to characterise TMJ lesions found in this species.Design Temporomandibular joints from fresh cadaver heads (n = 14) of California sea lions acquired from strandings were examined macroscopically and microscopically. The specimens were also evaluated for their mechanical and biochemical properties. Furthermore, if TMJ arthritic changes were present, joint characteristics were described and compared to healthy joints.Results Five male and 9 female specimens demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs in the TMJ. Out of the 9 female specimens, 4 specimens had TMJ lesions were seen either in the articular surface or the disc. Histologically, these pathologic specimens demonstrated subchondral bone defects, cartilage irregularities and inflammatory cell infiltrates. The normal TMJ discs did not exhibit significant direction dependence in tensile stiffness or strength in the rostrocaudal direction compared with the mediolateral direction among normal discs or discs from affected joints. The TMJ discs were not found to be anisotropic in tensile properties. This feature was further supported by randomly oriented collagen fibres as seen by electron microscopy. Furthermore, no significant differences were detected in biochemical composition of the discs dependent upon population.Conclusion The TMJ and its disc of the California sea lion exhibit similarities but also differences compared to other mammals with regards to structure-function relationships. A fibrous TMJ disc rich in collagen with minimal glycosaminoglycan content was characterised, and random fibre organisation was associated with isotropic mechanical properties in the central region of the disc.",
keywords = "California sea lion, Cartilage, Osteoarthritis, Temporomandibular joint, Zalophus californianus",
author = "Boaz Arzi and Murphy, {M. K.} and Leale, {D. M.} and {Vapniarsky Arzi}, Natalia and Verstraete, {Frank J}",
year = "2014",
doi = "10.1016/j.archoralbio.2014.09.004",
language = "English (US)",
volume = "60",
pages = "208--215",
journal = "Archives of Oral Biology",
issn = "0003-9969",
publisher = "Elsevier Limited",
number = "1",

}

TY - JOUR

T1 - The temporomandibular joint of California sea lions (Zalophus californianus)

T2 - Part 1 - Characterisation in health and disease

AU - Arzi, Boaz

AU - Murphy, M. K.

AU - Leale, D. M.

AU - Vapniarsky Arzi, Natalia

AU - Verstraete, Frank J

PY - 2014

Y1 - 2014

N2 - Objectives This study aimed to characterise the histologic, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of California sea lions. In addition, we sought to identify structure-function relationships and to characterise TMJ lesions found in this species.Design Temporomandibular joints from fresh cadaver heads (n = 14) of California sea lions acquired from strandings were examined macroscopically and microscopically. The specimens were also evaluated for their mechanical and biochemical properties. Furthermore, if TMJ arthritic changes were present, joint characteristics were described and compared to healthy joints.Results Five male and 9 female specimens demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs in the TMJ. Out of the 9 female specimens, 4 specimens had TMJ lesions were seen either in the articular surface or the disc. Histologically, these pathologic specimens demonstrated subchondral bone defects, cartilage irregularities and inflammatory cell infiltrates. The normal TMJ discs did not exhibit significant direction dependence in tensile stiffness or strength in the rostrocaudal direction compared with the mediolateral direction among normal discs or discs from affected joints. The TMJ discs were not found to be anisotropic in tensile properties. This feature was further supported by randomly oriented collagen fibres as seen by electron microscopy. Furthermore, no significant differences were detected in biochemical composition of the discs dependent upon population.Conclusion The TMJ and its disc of the California sea lion exhibit similarities but also differences compared to other mammals with regards to structure-function relationships. A fibrous TMJ disc rich in collagen with minimal glycosaminoglycan content was characterised, and random fibre organisation was associated with isotropic mechanical properties in the central region of the disc.

AB - Objectives This study aimed to characterise the histologic, biomechanical and biochemical properties of the temporomandibular joint (TMJ) of California sea lions. In addition, we sought to identify structure-function relationships and to characterise TMJ lesions found in this species.Design Temporomandibular joints from fresh cadaver heads (n = 14) of California sea lions acquired from strandings were examined macroscopically and microscopically. The specimens were also evaluated for their mechanical and biochemical properties. Furthermore, if TMJ arthritic changes were present, joint characteristics were described and compared to healthy joints.Results Five male and 9 female specimens demonstrated macroscopically normal fibrocartilaginous articular surfaces and fibrous discs in the TMJ. Out of the 9 female specimens, 4 specimens had TMJ lesions were seen either in the articular surface or the disc. Histologically, these pathologic specimens demonstrated subchondral bone defects, cartilage irregularities and inflammatory cell infiltrates. The normal TMJ discs did not exhibit significant direction dependence in tensile stiffness or strength in the rostrocaudal direction compared with the mediolateral direction among normal discs or discs from affected joints. The TMJ discs were not found to be anisotropic in tensile properties. This feature was further supported by randomly oriented collagen fibres as seen by electron microscopy. Furthermore, no significant differences were detected in biochemical composition of the discs dependent upon population.Conclusion The TMJ and its disc of the California sea lion exhibit similarities but also differences compared to other mammals with regards to structure-function relationships. A fibrous TMJ disc rich in collagen with minimal glycosaminoglycan content was characterised, and random fibre organisation was associated with isotropic mechanical properties in the central region of the disc.

KW - California sea lion

KW - Cartilage

KW - Osteoarthritis

KW - Temporomandibular joint

KW - Zalophus californianus

UR - http://www.scopus.com/inward/record.url?scp=84909579059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84909579059&partnerID=8YFLogxK

U2 - 10.1016/j.archoralbio.2014.09.004

DO - 10.1016/j.archoralbio.2014.09.004

M3 - Article

C2 - 25451464

AN - SCOPUS:84909579059

VL - 60

SP - 208

EP - 215

JO - Archives of Oral Biology

JF - Archives of Oral Biology

SN - 0003-9969

IS - 1

ER -