Abstract
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality in the United States. Most colorectal cancer patients die from advanced disease, and two-thirds of CRC deaths are due to liver metastases. Liver resection provides the best curative option for patients with colorectal liver metastases (CRLM), yet only 20% of those patients are eligible for liver metastases resection for curative intent. Loco-regional treatment of CRLM may provide additional benefits in terms of down-staging for resection and prolonged hepatic disease control. This review focusses on hepatic arterial infusion, radioembolization and chemoembolization.
Original language | English (US) |
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Pages (from-to) | 229-245 |
Number of pages | 17 |
Journal | Expert Review of Anticancer Therapy |
Volume | 16 |
Issue number | 2 |
DOIs | |
State | Published - Feb 1 2016 |
Externally published | Yes |
Keywords
- chemoembolization
- hepatic artery infusion
- liver metastases
- radioembolization
- Regional therapy
ASJC Scopus subject areas
- Oncology
- Pharmacology (medical)