Abstract
Colorectal cancer (CRC) is one of the leading causes of cancer-related mortality in the United States. Most colorectal cancer patients die from advanced disease, and two-thirds of CRC deaths are due to liver metastases. Liver resection provides the best curative option for patients with colorectal liver metastases (CRLM), yet only 20% of those patients are eligible for liver metastases resection for curative intent. Loco-regional treatment of CRLM may provide additional benefits in terms of down-staging for resection and prolonged hepatic disease control. This review focusses on hepatic arterial infusion, radioembolization and chemoembolization.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 229-245 |
| Number of pages | 17 |
| Journal | Expert Review of Anticancer Therapy |
| Volume | 16 |
| Issue number | 2 |
| DOIs | |
| State | Published - Feb 1 2016 |
| Externally published | Yes |
Keywords
- chemoembolization
- hepatic artery infusion
- liver metastases
- radioembolization
- Regional therapy
ASJC Scopus subject areas
- Oncology
- Pharmacology (medical)
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Cite this
Cho, M., Gong, J., & Fakih, M. (2016). The state of regional therapy in the management of metastatic colorectal cancer to the liver. Expert Review of Anticancer Therapy, 16(2), 229-245. https://doi.org/10.1586/14737140.2016.1129277