The second generation of the International Equine Gene Mapping Workshop half-sibling linkage map

G. Guérin, E. Bailey, D. Bernoco, I. Anderson, D. F. Antczak, K. Bell, I. Biros, G. Bjørnstad, A. T. Bowling, R. Brandon, A. R. Caetano, G. Cholewinski, D. Colling, M. Eggleston, N. Ellis, J. Flynn, B. Gralak, T. Hasegawa, M. Ketchum, G. LindgrenLeslie A Lyons, L. V. Millon, D. Mariat, J. Murray, A. Neau, K. Røed, K. Sandberg, L. C. Skow, I. Tammen, T. Tozaki, E. Van Dyk, B. Weiss, A. Young, J. Ziegle

Research output: Contribution to journalArticle

43 Scopus citations

Abstract

A low-density, male-based linkage map was constructed as one of the objectives of the International Equine Gene Mapping Workshop. Here we report the second generation map based on testing 503 half-sibling offspring from 13 sire families for 344 informative markers using the CRIMAP program. The multipoint linkage analysis localized 310 markers (90%) with 257 markers being linearly ordered. The map included 34 linkage groups representing all 31 autosomes and spanning 2262 cM with an average interval between loci of 10.1 cM. This map is a milestone in that it is the first map with linkage groups assigned to each of the 31 automosomes and a single linkage group to all but three chromosomes.

Original languageEnglish (US)
Pages (from-to)161-168
Number of pages8
JournalAnimal Genetics
Volume34
Issue number3
DOIs
StatePublished - Jun 2003

Keywords

  • Chromosome
  • Genome
  • Horse
  • Linkage group
  • Mapping
  • Markers
  • Microsatellite
  • Segregation

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Genetics
  • Genetics(clinical)

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    Guérin, G., Bailey, E., Bernoco, D., Anderson, I., Antczak, D. F., Bell, K., Biros, I., Bjørnstad, G., Bowling, A. T., Brandon, R., Caetano, A. R., Cholewinski, G., Colling, D., Eggleston, M., Ellis, N., Flynn, J., Gralak, B., Hasegawa, T., Ketchum, M., ... Ziegle, J. (2003). The second generation of the International Equine Gene Mapping Workshop half-sibling linkage map. Animal Genetics, 34(3), 161-168. https://doi.org/10.1046/j.1365-2052.2003.00973.x