The science and therapy of glucocorticoid-induced bone loss

Nancy E Lane, B. Lukert

Research output: Contribution to journalArticlepeer-review

180 Scopus citations


Glucocorticoids are critical in the management of chronic, noninfectious, inflammatory diseases. Bone loss is a most devastating side effect of these powerful medications. Glucocorticoids produce bone loss by altering calcium metabolism, suppressing gonadal hormone production, and inhibiting bone formation. Now that the mechanism of glucocorticoid-induced bone loss is understood and effective medications are available, this disease can be prevented and reversed.

Original languageEnglish (US)
Pages (from-to)465-483
Number of pages19
JournalEndocrinology and Metabolism Clinics of North America
Issue number2
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology
  • Biochemistry


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