The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts

Michael J. Mahan, Josep Casadesus, John R. Roth

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

We describe recJ mutants of Salmonella typhimurium. The recJ gene maps between sufD and serA (min 62) and is transcribed counterclockwise. Unlike recJ mutants of Escherichia coli, recJ strains of S. typhimurium are sensitive to irradiation with UV light. This sensitivity is equivalent to or greater that that displayed by recBCD mutant strains. The residual ability of phage P22 abc (anti-recBCD) mutants to form plaques on recBCD+ strains is eliminated in recJ hosts. Thus host RecJ function appears to substitute for the anti-RecBCD functions of phage P22 and may serve to limit RecBCD activity.

Original languageEnglish (US)
Pages (from-to)470-478
Number of pages9
JournalMGG Molecular & General Genetics
Volume232
Issue number3
DOIs
StatePublished - Apr 1992
Externally publishedYes

Fingerprint

Bacteriophage P22
Salmonella typhimurium
Salmonella
Bacteriophages
Ultraviolet Rays
Growth
Escherichia coli
Serum
Genes

Keywords

  • P22 anti-RecBC functions
  • recBCD
  • recJ
  • UV sensitivity

ASJC Scopus subject areas

  • Genetics

Cite this

The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts. / Mahan, Michael J.; Casadesus, Josep; Roth, John R.

In: MGG Molecular & General Genetics, Vol. 232, No. 3, 04.1992, p. 470-478.

Research output: Contribution to journalArticle

Mahan, Michael J. ; Casadesus, Josep ; Roth, John R. / The Salmonella typbimurium RecJ function permits growth of P22 abc phage on recBCD+ hosts. In: MGG Molecular & General Genetics. 1992 ; Vol. 232, No. 3. pp. 470-478.
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