The Role of Neurogenic Astroglial Cells in the Developing and Adult Central Nervous System

Stephen C Noctor, Lidija Ivic, Veronica Martinez-Cerdeno, Arnold R. Kriegstein

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

This chapter focuses on the role of neurogenic astroglial cells in the development of the central nervous system (CNS). Recent findings have elucidated a more complex role for astroglial cells in the development of CNS structures across many species. Mitotically active radial glial cells line the ventricular system throughout the developing CNS and have been shown to generate neocortical neurons in rodents. Precursor cells in the ventricular zone (VZ) can divide symmetrically or asymmetrically, and evidence indicates that both types of divisions coexist throughout the entire period of cortical neurogenesis.

Original languageEnglish (US)
Title of host publicationNeuroglia
PublisherOxford University Press
ISBN (Print)9780199865024, 0195152220, 9780195152227
DOIs
StatePublished - Sep 1 2013
Externally publishedYes

Keywords

  • Glial cells
  • Neurogenesis
  • Neurogenic glia
  • Radial glia cells

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

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