The role of growth hormone in T-cell development and reconstitution

Lisbeth A. Welniak, Rui Sun, William J Murphy

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

Growth hormone (GH), directly or through GH-induction of insulin-like growth factor (IGF)-1, has been implicated in lymphocyte development and function. Recent studies have questioned the role of GH and IGF-1 in immune responses. This review examines experimental data describing the immunoregulatory function of GH and attempts to reconcile the literature.

Original languageEnglish (US)
Pages (from-to)381-387
Number of pages7
JournalJournal of Leukocyte Biology
Volume71
Issue number3
StatePublished - Mar 1 2002
Externally publishedYes

Keywords

  • Deficiency
  • Dwarf
  • Neuroendocrine hormones
  • Thymus

ASJC Scopus subject areas

  • Cell Biology

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