@inproceedings{489f586dacf946bdaffff0641350f5d2,
title = "The role of Galectin-3 in stellate cell activation and liver fibrosis",
abstract = "Gal3 (galectin-3) has been known to be involved in the regulation of kidney, lung and liver fibrosis. We have reported a novel mechanism by which Gal3 contributes to fibrogenesis. Extracellular Gal3 is required for tethering of apoptotic bodies by HSC via cross-linking with integrin αvβ3, and consequently promoting HSC activation. On the other hand, phagocytosis induces Gal3 production by both HSC and Kupffer cells. Taken together, Gal3 may become a therapeutic target for antifibrogenic strategy.",
author = "Xiaosong Jiang and Xiangling Chen and Hiroo Fukada and Hsu, {Dan K.} and Fu-Tong Liu and Torok, {Natalia J}",
year = "2012",
month = dec,
day = "18",
doi = "10.1021/bk-2012-1115.ch023",
language = "English (US)",
isbn = "9780841228801",
volume = "1115",
series = "ACS Symposium Series",
publisher = "American Chemical Society",
pages = "391--395",
booktitle = "ACS Symposium Series",
}