The role of galanin in feeding behavior

Jacqueline Crawley

doi:10.1054/npep.1999.0049

The role of galanin in feeding behavior

Jacqueline Crawley

Research output: Contribution to journal › Article

125 Scopus citations

Abstract

Galanin inhibits food consumption in satiated rats. Discovered relatively recently is a 29-amino-acid neuropeptide, not homologous with any other known peptide. Three G-protein-linked galanin receptor subtypes have been cloned. This review summarizes the mechanisms by which exogenously administered galanin may stimulate ingestion, discusses pharmacological and genetic investigations of the role of endogenous galanin on feeding and body weight, and speculates on the therapeutic potential of non-peptide galanin receptor antagonists for the treatment of appetite disorders.

Original language	English (US)
Pages (from-to)	369-375
Number of pages	7
Journal	Neuropeptides
Volume	33
Issue number	5
DOIs	https://doi.org/10.1054/npep.1999.0049
State	Published - Oct 1999
Externally published	Yes

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ASJC Scopus subject areas

Endocrinology
Clinical Neurology
Endocrinology, Diabetes and Metabolism
Cellular and Molecular Neuroscience
Neuroscience(all)
Biochemistry

Cite this

Crawley, J. (1999). The role of galanin in feeding behavior. Neuropeptides, 33(5), 369-375. https://doi.org/10.1054/npep.1999.0049

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Access to Document

10.1054/npep.1999.0049