The role of bacteria in the blockage of biliary stents

Joseph Leung, T. K W Ling, J. L S Kung, J. Vallance-Owen

Research output: Contribution to journalArticle

144 Citations (Scopus)

Abstract

Recurrent jaundice and cholangitis due to stent occlusion by biliary sludge is a major complication of endoscopic stenting for malignant obstructive jaundice. Scanning electron microscopy study of the blocked stents revealed the sludge to consist of a mixture of bacteria and amorphous material. In vitro study using scanning electron microscopy demonstrated the attachment of bacteria to a segment of stent perfused with infected bile containing live bacteria. Associated with the microcolonies of bacteria was a collection of amorphous material forming a dense concretion on the surface of the stent. This phenomenon was not observed in experiments using sterile bile or with infected bile sterilized by formalin treatment or autoclaving. It was concluded that live bacteria are necessary for the initiation of biliary sludge formation which leads to subsequent stent blockage.

Original languageEnglish (US)
Pages (from-to)19-22
Number of pages4
JournalGastrointestinal Endoscopy
Volume34
Issue number1
StatePublished - 1988
Externally publishedYes

Fingerprint

Bile
Stents
Bacteria
Electron Scanning Microscopy
Cholangitis
Obstructive Jaundice
Sewage
Jaundice
Formaldehyde

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Leung, J., Ling, T. K. W., Kung, J. L. S., & Vallance-Owen, J. (1988). The role of bacteria in the blockage of biliary stents. Gastrointestinal Endoscopy, 34(1), 19-22.

The role of bacteria in the blockage of biliary stents. / Leung, Joseph; Ling, T. K W; Kung, J. L S; Vallance-Owen, J.

In: Gastrointestinal Endoscopy, Vol. 34, No. 1, 1988, p. 19-22.

Research output: Contribution to journalArticle

Leung, J, Ling, TKW, Kung, JLS & Vallance-Owen, J 1988, 'The role of bacteria in the blockage of biliary stents', Gastrointestinal Endoscopy, vol. 34, no. 1, pp. 19-22.
Leung J, Ling TKW, Kung JLS, Vallance-Owen J. The role of bacteria in the blockage of biliary stents. Gastrointestinal Endoscopy. 1988;34(1):19-22.
Leung, Joseph ; Ling, T. K W ; Kung, J. L S ; Vallance-Owen, J. / The role of bacteria in the blockage of biliary stents. In: Gastrointestinal Endoscopy. 1988 ; Vol. 34, No. 1. pp. 19-22.
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