The relationship between executive function and verbal memory in Parkinson's disease

Christopher I. Higginson, David S. King, Dawn Levine, Vicki L Wheelock, Nuny O. Khamphay, Karen A. Sigvardt

Research output: Contribution to journalArticle

65 Scopus citations

Abstract

A growing body of evidence suggests that the various cognitive symptoms found in Parkinson's disease (PD) are secondary to executive dysfunction. Studies addressing this possibility for memory impairment specifically have not included measures of working memory nor have they ruled-out potential mediating variables such as overall level of cognitive impairment or depression. The purpose of this study was to include measures of these variables in determining the relationship between multiple aspects of executive function and delayed verbal recall in 32 idiopathic PD patients. Results were consistent with the original hypothesis and further suggest that working memory is a key factor in recall memory and may mediate the relationship between other executive measures and recall in PD.

Original languageEnglish (US)
Pages (from-to)343-352
Number of pages10
JournalBrain and Cognition
Volume52
Issue number3
DOIs
StatePublished - Aug 2003

Keywords

  • Executive function
  • Parkinson's disease
  • Verbal memory
  • Working memory

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

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