TY - JOUR
T1 - The Relation of Fetal Age to the Character of Lesions in Fetal Lambs Infected with Brucella ovis
AU - Osburn, Bennie
PY - 1968/1/1
Y1 - 1968/1/1
N2 - Cultures of Brucella ovis were inoculated into the conceptus of ewes at various stages of gestation, and the fetal lambs were recovered from 10 to 81 days later. All lambs, the youngest of which was recovered on the 54th day of gestation, had lesions. The character of the lesions varied from that of reticuloendothelial hyperplasia and granulomatous inflammation in fetuses up to 91 days of gestation to that of a lymphoreticular nature with well-formed nodules of reticuloendothelial cells, lymphocytes, and plasma cells in older fetal lambs. It was suggested that the variation in the inflammatory response was attributable to the immaturity of the fetal immunologic system.
AB - Cultures of Brucella ovis were inoculated into the conceptus of ewes at various stages of gestation, and the fetal lambs were recovered from 10 to 81 days later. All lambs, the youngest of which was recovered on the 54th day of gestation, had lesions. The character of the lesions varied from that of reticuloendothelial hyperplasia and granulomatous inflammation in fetuses up to 91 days of gestation to that of a lymphoreticular nature with well-formed nodules of reticuloendothelial cells, lymphocytes, and plasma cells in older fetal lambs. It was suggested that the variation in the inflammatory response was attributable to the immaturity of the fetal immunologic system.
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U2 - 10.1177/030098586800500502
DO - 10.1177/030098586800500502
M3 - Article
C2 - 5752518
AN - SCOPUS:84964192951
VL - 5
SP - 395
EP - 406
JO - Pathologia veterinaria
JF - Pathologia veterinaria
SN - 0300-9858
IS - 5
ER -