The REFLECT statement: Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety

A. M. O'Connor, J. M. Sargeant, Ian Gardner, J. S. Dickson, M. E. Torrence, C. E. Dewey, I. R. Dohoo, R. B. Evans, J. T. Gray, M. Greiner, G. Keefe, S. L. Lefebvre, P. S. Morley, A. Ramirez, W. Sischo, D. R. Smith, K. Snedeker, J. Sofos, M. P. Ward, R. Wills

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes ptesents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A 2-day consensus meeting was held on November 18-19, 2008, in Chicago, Illinois, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web- based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines for Randomized Controlled Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.

Original languageEnglish (US)
Pages (from-to)18-26
Number of pages9
JournalJournal of Swine Health and Production
Volume18
Issue number1
StatePublished - Jan 1 2010
Externally publishedYes

Fingerprint

Food Safety
Livestock
food safety
Randomized Controlled Trials
livestock
Guidelines
livestock production
Checklist
methodology
terminology
Health
researchers
Terminology
Research Personnel

Keywords

  • Challenge studies
  • Livestock
  • Randomized trials
  • Standards

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology

Cite this

The REFLECT statement : Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety. / O'Connor, A. M.; Sargeant, J. M.; Gardner, Ian; Dickson, J. S.; Torrence, M. E.; Dewey, C. E.; Dohoo, I. R.; Evans, R. B.; Gray, J. T.; Greiner, M.; Keefe, G.; Lefebvre, S. L.; Morley, P. S.; Ramirez, A.; Sischo, W.; Smith, D. R.; Snedeker, K.; Sofos, J.; Ward, M. P.; Wills, R.

In: Journal of Swine Health and Production, Vol. 18, No. 1, 01.01.2010, p. 18-26.

Research output: Contribution to journalReview article

O'Connor, AM, Sargeant, JM, Gardner, I, Dickson, JS, Torrence, ME, Dewey, CE, Dohoo, IR, Evans, RB, Gray, JT, Greiner, M, Keefe, G, Lefebvre, SL, Morley, PS, Ramirez, A, Sischo, W, Smith, DR, Snedeker, K, Sofos, J, Ward, MP & Wills, R 2010, 'The REFLECT statement: Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety', Journal of Swine Health and Production, vol. 18, no. 1, pp. 18-26.
O'Connor, A. M. ; Sargeant, J. M. ; Gardner, Ian ; Dickson, J. S. ; Torrence, M. E. ; Dewey, C. E. ; Dohoo, I. R. ; Evans, R. B. ; Gray, J. T. ; Greiner, M. ; Keefe, G. ; Lefebvre, S. L. ; Morley, P. S. ; Ramirez, A. ; Sischo, W. ; Smith, D. R. ; Snedeker, K. ; Sofos, J. ; Ward, M. P. ; Wills, R. / The REFLECT statement : Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety. In: Journal of Swine Health and Production. 2010 ; Vol. 18, No. 1. pp. 18-26.
@article{c6444f4852d4420a87d02a004818f052,
title = "The REFLECT statement: Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety",
abstract = "The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes ptesents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A 2-day consensus meeting was held on November 18-19, 2008, in Chicago, Illinois, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web- based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines for Randomized Controlled Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.",
keywords = "Challenge studies, Livestock, Randomized trials, Standards",
author = "O'Connor, {A. M.} and Sargeant, {J. M.} and Ian Gardner and Dickson, {J. S.} and Torrence, {M. E.} and Dewey, {C. E.} and Dohoo, {I. R.} and Evans, {R. B.} and Gray, {J. T.} and M. Greiner and G. Keefe and Lefebvre, {S. L.} and Morley, {P. S.} and A. Ramirez and W. Sischo and Smith, {D. R.} and K. Snedeker and J. Sofos and Ward, {M. P.} and R. Wills",
year = "2010",
month = "1",
day = "1",
language = "English (US)",
volume = "18",
pages = "18--26",
journal = "Journal of Swine Health and Production",
issn = "1537-209X",
publisher = "American Association of Swine Veterinarians",
number = "1",

}

TY - JOUR

T1 - The REFLECT statement

T2 - Methods and processes of creating reporting guidelines for randomized controlled trials for livestock and food safety

AU - O'Connor, A. M.

AU - Sargeant, J. M.

AU - Gardner, Ian

AU - Dickson, J. S.

AU - Torrence, M. E.

AU - Dewey, C. E.

AU - Dohoo, I. R.

AU - Evans, R. B.

AU - Gray, J. T.

AU - Greiner, M.

AU - Keefe, G.

AU - Lefebvre, S. L.

AU - Morley, P. S.

AU - Ramirez, A.

AU - Sischo, W.

AU - Smith, D. R.

AU - Snedeker, K.

AU - Sofos, J.

AU - Ward, M. P.

AU - Wills, R.

PY - 2010/1/1

Y1 - 2010/1/1

N2 - The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes ptesents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A 2-day consensus meeting was held on November 18-19, 2008, in Chicago, Illinois, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web- based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines for Randomized Controlled Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.

AB - The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes ptesents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A 2-day consensus meeting was held on November 18-19, 2008, in Chicago, Illinois, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web- based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines for Randomized Controlled Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.

KW - Challenge studies

KW - Livestock

KW - Randomized trials

KW - Standards

UR - http://www.scopus.com/inward/record.url?scp=76749145264&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=76749145264&partnerID=8YFLogxK

M3 - Review article

AN - SCOPUS:76749145264

VL - 18

SP - 18

EP - 26

JO - Journal of Swine Health and Production

JF - Journal of Swine Health and Production

SN - 1537-209X

IS - 1

ER -