The REFLECT statement: Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety

A. M. O'Connor, J. M. Sargeant, Ian Gardner, J. S. Dickson, M. E. Torrence, C. E. Dewey, I. R. Dohoo, R. B. Evans, J. T. Gray, M. Greiner, G. Keefe, S. L. Lefebvre, P. S. Morley, A. Ramirez, W. Sischo, D. R. Smith, K. Snedeker, J. Sofos, M. P. Ward, R. Wills

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

The conduct of randomized controlled trials in livestock with production, health, and food-safety outcomes presents unique challenges that may not be adequately reported in trial reports. The objective of this project was to modify the CONSORT (Consolidated Standards of Reporting Trials) statement to reflect the unique aspects of reporting these livestock trials. A two-day consensus meeting was held on November 18-19, 2008 in Chicago, IL, United States of America, to achieve the objective. Prior to the meeting, a Web-based survey was conducted to identify issues for discussion. The 24 attendees were biostatisticians, epidemiologists, food-safety researchers, livestock-production specialists, journal editors, assistant editors, and associate editors. Prior to the meeting, the attendees completed a Web-based survey indicating which CONSORT statement items may need to be modified to address unique issues for livestock trials. The consensus meeting resulted in the production of the REFLECT (Reporting Guidelines For Randomized Control Trials) statement for livestock and food safety (LFS) and 22-item checklist. Fourteen items were modified from the CONSORT checklist, and an additional sub-item was proposed to address challenge trials. The REFLECT statement proposes new terminology, more consistent with common usage in livestock production, to describe study subjects. Evidence was not always available to support modification to or inclusion of an item. The use of the REFLECT statement, which addresses issues unique to livestock trials, should improve the quality of reporting and design for trials reporting production, health, and food-safety outcomes.

Original languageEnglish (US)
Pages (from-to)11-18
Number of pages8
JournalPreventive Veterinary Medicine
Volume93
Issue number1
DOIs
StatePublished - Jan 1 2010

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Food Safety
Livestock
food safety
Randomized Controlled Trials
livestock
Guidelines
livestock production
Checklist
methodology
terminology
Health
researchers
Terminology
Research Personnel

Keywords

  • Challenge studies
  • Livestock
  • Randomized trials
  • Standards

ASJC Scopus subject areas

  • Food Animals
  • Animal Science and Zoology

Cite this

The REFLECT statement : Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety. / O'Connor, A. M.; Sargeant, J. M.; Gardner, Ian; Dickson, J. S.; Torrence, M. E.; Dewey, C. E.; Dohoo, I. R.; Evans, R. B.; Gray, J. T.; Greiner, M.; Keefe, G.; Lefebvre, S. L.; Morley, P. S.; Ramirez, A.; Sischo, W.; Smith, D. R.; Snedeker, K.; Sofos, J.; Ward, M. P.; Wills, R.

In: Preventive Veterinary Medicine, Vol. 93, No. 1, 01.01.2010, p. 11-18.

Research output: Contribution to journalArticle

O'Connor, AM, Sargeant, JM, Gardner, I, Dickson, JS, Torrence, ME, Dewey, CE, Dohoo, IR, Evans, RB, Gray, JT, Greiner, M, Keefe, G, Lefebvre, SL, Morley, PS, Ramirez, A, Sischo, W, Smith, DR, Snedeker, K, Sofos, J, Ward, MP & Wills, R 2010, 'The REFLECT statement: Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety', Preventive Veterinary Medicine, vol. 93, no. 1, pp. 11-18. https://doi.org/10.1016/j.prevetmed.2009.10.008
O'Connor, A. M. ; Sargeant, J. M. ; Gardner, Ian ; Dickson, J. S. ; Torrence, M. E. ; Dewey, C. E. ; Dohoo, I. R. ; Evans, R. B. ; Gray, J. T. ; Greiner, M. ; Keefe, G. ; Lefebvre, S. L. ; Morley, P. S. ; Ramirez, A. ; Sischo, W. ; Smith, D. R. ; Snedeker, K. ; Sofos, J. ; Ward, M. P. ; Wills, R. / The REFLECT statement : Methods and processes of creating Reporting Guidelines For Randomized Controlled Trials for livestock and food safety. In: Preventive Veterinary Medicine. 2010 ; Vol. 93, No. 1. pp. 11-18.
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