Abstract
Recent developments in basic research suggest that therapeutic breakthroughs may occur in Alzheimer's disease treatment over the coming decades. To model the potential magnitude and nature of the effect of these advances, historical data from congestive heart failure and Parkinson's disease were used. Projections indicate that therapies which delay disease onset will markedly reduce overall disease prevalence, whereas therapies to treat existing disease will alter the proportion of cases that are mild as opposed to moderate/severe. The public health impact of such changes would likely involve both the amount and type of health services needed. Particularly likely to arise are new forms of outpatient services, such as disease-specific clinics and centers. None of our models predicts less than a threefold rise in the total number of persons with Alzheimer's disease between 2000 and 2050. Therefore, Alzheimer's care is likely to remain a major public health problem during the coming decades.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 213-231 |
| Number of pages | 19 |
| Journal | Annual Review of Public Health |
| Volume | 23 |
| DOIs | |
| State | Published - 2002 |
| Externally published | Yes |
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Keywords
- Alzheimer's care
- Alzheimer's disease
- Public health impact
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
Cite this
The public health impact of Alzheimer's disease, 2000-2050 : Potential implication of treatment advances. / Sloane, Philip D.; Zimmerman, Sheryl; Suchindran, Chirayath; Reed, Peter; Wang, Lily; Boustani, Malaz; Sudha, S.
In: Annual Review of Public Health, Vol. 23, 2002, p. 213-231.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The public health impact of Alzheimer's disease, 2000-2050
T2 - Potential implication of treatment advances
AU - Sloane, Philip D.
AU - Zimmerman, Sheryl
AU - Suchindran, Chirayath
AU - Reed, Peter
AU - Wang, Lily
AU - Boustani, Malaz
AU - Sudha, S.
PY - 2002
Y1 - 2002
N2 - Recent developments in basic research suggest that therapeutic breakthroughs may occur in Alzheimer's disease treatment over the coming decades. To model the potential magnitude and nature of the effect of these advances, historical data from congestive heart failure and Parkinson's disease were used. Projections indicate that therapies which delay disease onset will markedly reduce overall disease prevalence, whereas therapies to treat existing disease will alter the proportion of cases that are mild as opposed to moderate/severe. The public health impact of such changes would likely involve both the amount and type of health services needed. Particularly likely to arise are new forms of outpatient services, such as disease-specific clinics and centers. None of our models predicts less than a threefold rise in the total number of persons with Alzheimer's disease between 2000 and 2050. Therefore, Alzheimer's care is likely to remain a major public health problem during the coming decades.
AB - Recent developments in basic research suggest that therapeutic breakthroughs may occur in Alzheimer's disease treatment over the coming decades. To model the potential magnitude and nature of the effect of these advances, historical data from congestive heart failure and Parkinson's disease were used. Projections indicate that therapies which delay disease onset will markedly reduce overall disease prevalence, whereas therapies to treat existing disease will alter the proportion of cases that are mild as opposed to moderate/severe. The public health impact of such changes would likely involve both the amount and type of health services needed. Particularly likely to arise are new forms of outpatient services, such as disease-specific clinics and centers. None of our models predicts less than a threefold rise in the total number of persons with Alzheimer's disease between 2000 and 2050. Therefore, Alzheimer's care is likely to remain a major public health problem during the coming decades.
KW - Alzheimer's care
KW - Alzheimer's disease
KW - Public health impact
UR - http://www.scopus.com/inward/record.url?scp=0036250657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036250657&partnerID=8YFLogxK
U2 - 10.1146/annurev.publhealth.23.100901.140525
DO - 10.1146/annurev.publhealth.23.100901.140525
M3 - Article
C2 - 11910061
AN - SCOPUS:0036250657
VL - 23
SP - 213
EP - 231
JO - Annual Review of Public Health
JF - Annual Review of Public Health
SN - 0163-7525
ER -