The progressive nature of subaortic stenosis in congenital heart disease

Robert M. Freedom, Andrew N Pelech, Abe Brand, Michael Vogel, Peter M. Olley, Jeffrey Smallhorn, Richard D. Rowe

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Data derived from serial hemodynamic and angiocardiographic investigations on pediatric patients not subjected to intervening intracardiac operations support the view that subaortic stenosis in congenital heart disease tends to be a progressive disorder. Our data are obtained from two groups of patients. The first comprised 22 patients with discrete subaortic stenosis in relative isolation. The second was made up of 19 patients with the fibrous or fibromuscular forms of discrete subaortic stenosis associated with a perimembranous ventricular septal defect. The results from both groups support our initial contention. The progressive character of subaortic stenosis in these two situations illustrates the dynamic nature of congenital heart disease, and the tendency of a changing form and function.

Original languageEnglish (US)
Pages (from-to)137-143
Number of pages7
JournalInternational Journal of Cardiology
Volume8
Issue number2
DOIs
StatePublished - 1985
Externally publishedYes

Fingerprint

Heart Diseases
Discrete Subaortic Stenosis
Pathologic Constriction
Ventricular Heart Septal Defects
Hemodynamics
Pediatrics

Keywords

  • congenital heart disease
  • heart defects
  • natural history
  • subaortic diaphragmatic shelf
  • ventricular septal defect

ASJC Scopus subject areas

  • Medicine(all)
  • Cardiology and Cardiovascular Medicine

Cite this

The progressive nature of subaortic stenosis in congenital heart disease. / Freedom, Robert M.; Pelech, Andrew N; Brand, Abe; Vogel, Michael; Olley, Peter M.; Smallhorn, Jeffrey; Rowe, Richard D.

In: International Journal of Cardiology, Vol. 8, No. 2, 1985, p. 137-143.

Research output: Contribution to journalArticle

Freedom, Robert M. ; Pelech, Andrew N ; Brand, Abe ; Vogel, Michael ; Olley, Peter M. ; Smallhorn, Jeffrey ; Rowe, Richard D. / The progressive nature of subaortic stenosis in congenital heart disease. In: International Journal of Cardiology. 1985 ; Vol. 8, No. 2. pp. 137-143.
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