The pathology of the claustrum in Galloway syndrome indicates the existence of claustro-entorhinal pathway.

J. Moryś, Matthew Bobinski, P. Kozłowski, J. Dziewiatkowski, A. Switka, H. Wiśniewski, O. Narkiewicz

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The morphology of the claustrum in Galloway syndrome was investigated. Galloway syndrome is a rare autosomal recessive disease that causes microcephaly and is associated with kidney pathology. The brain examined was small, and the external surface of the hemispheres was lissencephalic, with an abnormal gyrification pattern. The whole cerebral cortex showed severe pathological changes, but the most affected area was the cortex lying on the medial aspect of the temporal lobe, especially the entorhinal cortex. In addition, the paraamygdalar and temporal parts of the claustrum were intensively changed. These results may confirm the opinion that the claustrum is a cortico-dependent structure and that the limbic cortex receives large projection from its ventral parts.

Original languageEnglish (US)
Pages (from-to)1-9
Number of pages9
JournalFolia Morphologica
Volume52
Issue number1
StatePublished - 1993
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology
  • Anatomy
  • Embryology
  • Histology
  • Neuroscience(all)

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    Moryś, J., Bobinski, M., Kozłowski, P., Dziewiatkowski, J., Switka, A., Wiśniewski, H., & Narkiewicz, O. (1993). The pathology of the claustrum in Galloway syndrome indicates the existence of claustro-entorhinal pathway. Folia Morphologica, 52(1), 1-9.