The pathogenesis of vesicular stomatitis virus, serotype Indiana, in Aedes aegypti mosquitoes. I. Intrathoracic injection

Irwin Liu, Y. C. Zee

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Analysis of infectious virus particles after intrathoracic injection revealed that Aedes aegypti mosquito tissues are capable of supporting the growth of vesicular stomatitis virus (VSV), serotype Indiana. Although all tissues assayed (salivary gland, midgut, diverticulum, malphigian tubules, and ovary) were capable of supporting VSV growth, the salivary gland was the only organ capable of maintaining an appreciable amount of virus for periods longer than 9 days postinfection. Electron microscopic studies of infected tissues showed virus particles consistently within the cell cytoplasm of all organs with no evidence of nuclear involvement. Direct evidence of crystalline formation of VSV in the apical cavities of salivary gland tissue was demonstrated.

Original languageEnglish (US)
Pages (from-to)177-185
Number of pages9
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume25
Issue number1
DOIs
StatePublished - Jan 1 1976

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Vesicular stomatitis Indiana virus
Aedes
Culicidae
Vesicular Stomatitis
Injections
Salivary Glands
Virion
Viruses
Diverticulum
Growth
Cytomegalovirus
Ovary
Cytoplasm
Electrons
Serogroup

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

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