The pathogenesis of retinal dysplasia

Arthur M. Silverstein, Bennie Osburn, Robert A. Prendergast

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Retinal dysplasia may be found in association with a variety of congenital abnormalities of the eye, some genetically transmitted and others due to exogenous influences. The dysplasias due to retinal hyperplasia, to retinal detachment or failure of coaptation, or to congenital absence of pigment epithelium suggest that orderly retinal morphogenesis may depend upon the organizing influence of an adjacent pigment epithelium. Dysplasia may also result from a necrotizing inflammatory response of the retina to infection, resulting in disorganization and abortive repair rather than true dysgenesis.

Original languageEnglish (US)
Pages (from-to)13-21
Number of pages9
JournalAmerican Journal of Ophthalmology
Volume72
Issue number1
DOIs
StatePublished - Jan 1 1971
Externally publishedYes

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ASJC Scopus subject areas

  • Ophthalmology

Cite this

Silverstein, A. M., Osburn, B., & Prendergast, R. A. (1971). The pathogenesis of retinal dysplasia. American Journal of Ophthalmology, 72(1), 13-21. https://doi.org/10.1016/0002-9394(71)91586-8