Abstract
Retinal dysplasia may be found in association with a variety of congenital abnormalities of the eye, some genetically transmitted and others due to exogenous influences. The dysplasias due to retinal hyperplasia, to retinal detachment or failure of coaptation, or to congenital absence of pigment epithelium suggest that orderly retinal morphogenesis may depend upon the organizing influence of an adjacent pigment epithelium. Dysplasia may also result from a necrotizing inflammatory response of the retina to infection, resulting in disorganization and abortive repair rather than true dysgenesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 13-21 |
| Number of pages | 9 |
| Journal | American Journal of Ophthalmology |
| Volume | 72 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 1971 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Ophthalmology
Cite this
The pathogenesis of retinal dysplasia. / Silverstein, Arthur M.; Osburn, Bennie; Prendergast, Robert A.
In: American Journal of Ophthalmology, Vol. 72, No. 1, 01.01.1971, p. 13-21.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The pathogenesis of retinal dysplasia
AU - Silverstein, Arthur M.
AU - Osburn, Bennie
AU - Prendergast, Robert A.
PY - 1971/1/1
Y1 - 1971/1/1
N2 - Retinal dysplasia may be found in association with a variety of congenital abnormalities of the eye, some genetically transmitted and others due to exogenous influences. The dysplasias due to retinal hyperplasia, to retinal detachment or failure of coaptation, or to congenital absence of pigment epithelium suggest that orderly retinal morphogenesis may depend upon the organizing influence of an adjacent pigment epithelium. Dysplasia may also result from a necrotizing inflammatory response of the retina to infection, resulting in disorganization and abortive repair rather than true dysgenesis.
AB - Retinal dysplasia may be found in association with a variety of congenital abnormalities of the eye, some genetically transmitted and others due to exogenous influences. The dysplasias due to retinal hyperplasia, to retinal detachment or failure of coaptation, or to congenital absence of pigment epithelium suggest that orderly retinal morphogenesis may depend upon the organizing influence of an adjacent pigment epithelium. Dysplasia may also result from a necrotizing inflammatory response of the retina to infection, resulting in disorganization and abortive repair rather than true dysgenesis.
UR - http://www.scopus.com/inward/record.url?scp=0015245673&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015245673&partnerID=8YFLogxK
U2 - 10.1016/0002-9394(71)91586-8
DO - 10.1016/0002-9394(71)91586-8
M3 - Article
C2 - 4328353
AN - SCOPUS:0015245673
VL - 72
SP - 13
EP - 21
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 1
ER -