Abstract
The pars tuberalis and pars distalis are constant subdivisions of the vertebrate adenohypophysis. Unlike the pars distalis, however, direct evidence of an endocrine function for the pars tuberalis is lacking. The present immunocytochemical study shows that ovine pars tuberalis to be unique in that 1) its only immunoreactive hormone-containing cell type is the gonadotrope; and 2) the vast majority of pars tuberalis cells contain no identifiable pituitary hormones. In vitro superfusion studies demonstrate that the ovine pars tuberalis is capable of baseline and GnRH-stimulated gonadotropin secretion which, on a per mg basis, is qualitatively and quantitatively similar to the secretory capacity of the pars distalis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2084-2091 |
| Number of pages | 8 |
| Journal | Endocrinology |
| Volume | 114 |
| Issue number | 6 |
| State | Published - 1984 |
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ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
The ovine pars tuberalis : A naturally occurring source of partially purified gonadotropes which secrete luteinizing hormone in vitro. / Gross, D. S.; Turgeon, Judith L; Waring, D. W.
In: Endocrinology, Vol. 114, No. 6, 1984, p. 2084-2091.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The ovine pars tuberalis
T2 - A naturally occurring source of partially purified gonadotropes which secrete luteinizing hormone in vitro
AU - Gross, D. S.
AU - Turgeon, Judith L
AU - Waring, D. W.
PY - 1984
Y1 - 1984
N2 - The pars tuberalis and pars distalis are constant subdivisions of the vertebrate adenohypophysis. Unlike the pars distalis, however, direct evidence of an endocrine function for the pars tuberalis is lacking. The present immunocytochemical study shows that ovine pars tuberalis to be unique in that 1) its only immunoreactive hormone-containing cell type is the gonadotrope; and 2) the vast majority of pars tuberalis cells contain no identifiable pituitary hormones. In vitro superfusion studies demonstrate that the ovine pars tuberalis is capable of baseline and GnRH-stimulated gonadotropin secretion which, on a per mg basis, is qualitatively and quantitatively similar to the secretory capacity of the pars distalis.
AB - The pars tuberalis and pars distalis are constant subdivisions of the vertebrate adenohypophysis. Unlike the pars distalis, however, direct evidence of an endocrine function for the pars tuberalis is lacking. The present immunocytochemical study shows that ovine pars tuberalis to be unique in that 1) its only immunoreactive hormone-containing cell type is the gonadotrope; and 2) the vast majority of pars tuberalis cells contain no identifiable pituitary hormones. In vitro superfusion studies demonstrate that the ovine pars tuberalis is capable of baseline and GnRH-stimulated gonadotropin secretion which, on a per mg basis, is qualitatively and quantitatively similar to the secretory capacity of the pars distalis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021251225&partnerID=8YFLogxK
M3 - Article
C2 - 6426936
AN - SCOPUS:0021251225
VL - 114
SP - 2084
EP - 2091
JO - Endocrinology
JF - Endocrinology
SN - 0013-7227
IS - 6
ER -